The past decade has seen significant advances in our understanding of Hedgehog (HH)
signaling pathway in various biological events. HH signaling pathway exerts its biological …

Primary cilia project in a single copy from the surface of most vertebrate cell types; they
detect and transmit extracellular cues to regulate diverse cellular processes during …

Wnt signaling plays a major role in regulating cell proliferation and differentiation. The Wnt
ligands are a family of 19 secreted glycoproteins that mediate their signaling effects via …

Simple Summary The Hedgehog/GLI (Hh/GLI) pathway plays a major role during
development and it is commonly dysregulated in many diseases, including cancer. This …

The Hedgehog-GLI (HH-GLI) pathway is a highly conserved signaling that plays a critical
role in controlling cell specification, cell–cell interaction and tissue patterning during …

Cell-cell communication through evolutionarily conserved signaling pathways governs
embryonic development and adult tissue homeostasis. Deregulation of these signaling …

The cloning of the founding member of the Hedgehog (HH) family of secreted proteins two
decades ago inaugurated a field that has diversified to encompass embryonic development …

The hedgehog (HH) signaling pathway regulates normal cell growth and differentiation. As a
consequence of improper control, aberrant HH signaling results in tumorigenesis and …

Signaling pathways that mediate cell-cell communication are essential for collective cell
behaviors in multicellular systems. The hedgehog (HH) pathway, first discovered and …

Motor neurons (MNs) are neuronal cells located in the central nervous system (CNS)
controlling a variety of downstream targets. This function infers the existence of MN subtypes …