Decades of evidence across taxa have established the importance of dopamine (DA)
signaling in the pFC for successful working memory performance. Genetic and hormonal …

The aim of this systematic review was to qualitatively synthesise the available research that
investigated the influence of COMT genotype at SNP rs4680 on both task‐based and resting …

Hypnotizability is a stable trait that moderates the benefit of hypnosis for treating pain, but
limited availability of hypnotizability testing deters widespread use of hypnosis. Inexpensive …

Treatment-resistant schizophrenia (TRS) continues to be a challenge. It was related to
different factors, including alterations in the activity of brain dopaminergic system, which …

Some people are more willing to make immediate, risky, or costly reward-focused choices
than others, which has been hypothesized to be associated with individual differences in …

Abstract Catechol-O-methyltransferase (COMT) enzyme has a major role in the adjustment
of catechol-dependent functions, for example, cognition, cardiac function, and pain …

Background/objective Raloxifene, a selective estrogen receptor modulator (SERM), may
improve symptoms and cognition in schizophrenia spectrum disorders (SSD). Studies have …

Objective Schizophrenia is a multifaceted mental disorder characterized by heterogeneous
positive/negative symptoms and cognitive deficits. Sex differences have been reported in …

Pharmacogenetic markers are current targets for the personalized treatment of psychosis.
Limited data exist on COMT and NRG1 polymorphisms in relation to risperidone treatment …

Previous findings have indicated that catechol-O-methyltransferase (COMT) may be a
genetic risk factor for chemobrain. However, the mediation of chemobrain by COMT …