One is not enough: understanding and modeling polysubstance use

EA Crummy, TJ O'Neal, BM Baskin… - Frontiers in …, 2020 - frontiersin.org
Substance use disorder (SUD) is a chronic, relapsing disease with a highly multifaceted
pathology that includes (but is not limited to) sensitivity to drug-associated cues, negative …

Co-use of alcohol and cannabis: A review

AM Yurasek, ER Aston, J Metrik - Current addiction reports, 2017 - Springer
Abstract Purpose of Review The purpose of this review is to provide an overview of the
existing literature on the relationship between the co-use of cannabis and alcohol including …

Simultaneous versus concurrent use of alcohol and cannabis in the National Alcohol Survey

MS Subbaraman, WC Kerr - Alcoholism: clinical and …, 2015 - Wiley Online Library
Background Cannabis is the most commonly used drug among those who drink, yet no
study has directly compared those who use cannabis and alcohol simultaneously versus …

Patterns of cannabis and alcohol co-use: Substitution versus complementary effects

RL Gunn, ER Aston, J Metrik - Alcohol Research: Current …, 2022 - pmc.ncbi.nlm.nih.gov
PURPOSE The purpose of this review is to discuss the literature regarding the concurrent
use (co-use) of alcohol and cannabis and competing hypotheses as to whether cannabis …

Role of cannabis in cardiovascular disorders

H Goyal, HH Awad, JK Ghali - Journal of thoracic disease, 2017 - pmc.ncbi.nlm.nih.gov
The growing popularity of medical and recreational consumption of cannabis, especially
among the youth, raises immediate concerns regarding its safety and long-terms effects. The …

The effects of cannabis and alcohol on simulated driving: Influences of dose and experience

LA Downey, R King, K Papafotiou, P Swann… - Accident Analysis & …, 2013 - Elsevier
BACKGROUND: Cannabis and alcohol are the most popular drugs amongst recreational
users, and most prevalent in injured and deceased drivers. Clarification of the interactive …

Daily patterns of marijuana and alcohol co‐use among individuals with alcohol and cannabis use disorders

J Metrik, RL Gunn, KM Jackson… - Alcoholism: Clinical …, 2018 - Wiley Online Library
Background The study aims were to examine daily associations between marijuana and
alcohol use and the extent to which the association differs as a function of cannabis use …

Human laboratory studies on cannabinoids and psychosis

M Sherif, R Radhakrishnan, DC D'Souza… - Biological …, 2016 - Elsevier
Some of the most compelling evidence supporting an association between cannabinoid
agonists and psychosis comes from controlled laboratory studies in humans. Randomized …

Pharmacokinetic and pharmacodynamic drug interactions with ethanol (alcohol)

LN Chan, GD Anderson - Clinical pharmacokinetics, 2014 - Springer
Ethanol (alcohol) is one of the most widely used legal drugs in the world. Ethanol is
metabolized by alcohol dehydrogenase (ADH) and the cytochrome P450 (CYP) 2E1 drug …