Metabolic messengers: tumour necrosis factor

JK Sethi, GS Hotamisligil - Nature metabolism, 2021 - nature.com
Tumour necrosis factor (TNF) is a classical, pleiotropic pro-inflammatory cytokine. It is also
the first 'adipokine'described to be produced from adipose tissue, regulated in obesity and …

Inflammation, metaflammation and immunometabolic disorders

GS Hotamisligil - Nature, 2017 - nature.com
Proper regulation and management of energy, substrate diversity and quantity, as well as
macromolecular synthesis and breakdown processes, are fundamental to cellular and …

Recent advances in neuropeptide signaling in Drosophila, from genes to physiology and behavior

DR Nässel, M Zandawala - Progress in neurobiology, 2019 - Elsevier
This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

[HTML][HTML] Macrophages in obesity and non-alcoholic fatty liver disease: Crosstalk with metabolism

S Lefere, F Tacke - JHEP reports, 2019 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver disease worldwide, and
a major cause of liver cirrhosis and hepatocellular carcinoma. NAFLD is intimately linked …

Fat body biology in the last decade

S Li, X Yu, Q Feng - Annual Review of Entomology, 2019 - annualreviews.org
The insect fat body is analogous to vertebrate adipose tissue and liver. In this review, the
new and exciting advancements made in fat body biology in the last decade are …

Regulation of body size and growth control

MJ Texada, T Koyama, K Rewitz - Genetics, 2020 - academic.oup.com
The control of body and organ growth is essential for the development of adults with proper
size and proportions, which is important for survival and reproduction. In animals, adult body …

Fat body—Multifunctional insect tissue

P Skowronek, Ł Wójcik, A Strachecka - Insects, 2021 - mdpi.com
Simple Summary Efficient and proper functioning of processes within living organisms play
key roles in times of climate change and strong human pressure. In insects, the most …

Drosophila as a model to study obesity and metabolic disease

LP Musselman, RP Kühnlein - Journal of Experimental …, 2018 - journals.biologists.com
Excess adipose fat accumulation, or obesity, is a growing problem worldwide in terms of
both the rate of incidence and the severity of obesity-associated metabolic disease. Adipose …

Triacylglycerol Metabolism in Drosophila melanogaster

C Heier, RP Kühnlein - Genetics, 2018 - academic.oup.com
Triacylglycerol (TAG) is the most important caloric source with respect to energy
homeostasis in animals. In addition to its evolutionarily conserved importance as an energy …

Metabolism and growth adaptation to environmental conditions in Drosophila

T Koyama, MJ Texada, KA Halberg… - Cellular and Molecular Life …, 2020 - Springer
Organisms adapt to changing environments by adjusting their development, metabolism,
and behavior to improve their chances of survival and reproduction. To achieve such …