Global challenges in preparedness and response to epidemic infectious diseases

P Olliaro, E Torreele - Molecular Therapy, 2022‏ - cell.com
Lessons drawn from successes and failures with coronavirus disease 2019 (COVID-19) and
Ebola virus disease (EVD) should help sha** a robust health innovation system for …

Gaps and opportunities in sepsis translational research

JC Marshall, A Leligdowicz - EBioMedicine, 2022‏ - thelancet.com
Infection initiates sepsis, but the clinical disease arises through the innate immune response
of the host. A rapidly evolving understanding of the biology of that response has not been …

Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19

C Kartsonaki, JK Baillie, NG Barrio… - International journal …, 2023‏ - academic.oup.com
Background We describe demographic features, treatments and clinical outcomes in the
International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) COVID …

ISARIC-COVID-19 dataset: a prospective, standardized, global dataset of patients hospitalized with COVID-19

M Etienne, N Ettalhaoui, AG Everding, M Evers, I Fabre… - Scientific data, 2022‏ - nature.com
Abstract The International Severe Acute Respiratory and Emerging Infection Consortium
(ISARIC) COVID-19 dataset is one of the largest international databases of prospectively …

Association between sex hormone levels and clinical outcomes in patients with COVID-19 admitted to hospital: an observational, retrospective, cohort study

A Beltrame, P Salguero, E Rossi, A Conesa… - Frontiers in …, 2022‏ - frontiersin.org
Understanding the cause of sex disparities in COVID-19 outcomes is a major challenge. We
investigate sex hormone levels and their association with outcomes in COVID-19 patients …

Sex differences in post-acute neurological sequelae of SARS-CoV-2 and symptom resolution in adults after coronavirus disease 2019 hospitalization: an international …

SM Cho, L Premraj, D Battaglini… - Brain …, 2024‏ - academic.oup.com
Although it is known that coronavirus disease 2019 can present with a range of neurological
manifestations and in-hospital complications, sparse data exist on whether these initial …

[HTML][HTML] Creation of standardized common data elements for diagnostic tests in infectious disease studies: semantic and syntactic map**

C Stellmach, SM Hopff, T Jaenisch… - Journal of Medical …, 2024‏ - jmir.org
Background It is necessary to harmonize and standardize data variables used in case report
forms (CRFs) of clinical studies to facilitate the merging and sharing of the collected patient …

Lightweight transformers for clinical natural language processing

O Rohanian, M Nouriborji, H Jauncey… - Natural language …, 2024‏ - cambridge.org
Specialised pre-trained language models are becoming more frequent in Natural language
Processing (NLP) since they can potentially outperform models trained on generic texts …

Monkeypox: how will we know if the treatments work?

A Rojek, J Dunning, P Olliaro - The Lancet. Infectious …, 2022‏ - pmc.ncbi.nlm.nih.gov
The challenging work to find primary outcomes that reflect the diversity of disease and meet
the needs of patients, regulators, and public health officials is underway. It is uncertain …

A comparison of four epidemic waves of COVID-19 in Malawi; an observational cohort study

C Anscombe, S Lissauer, H Thole, J Rylance… - BMC Infectious …, 2023‏ - Springer
Background Compared to the abundance of clinical and genomic information available on
patients hospitalised with COVID-19 disease from high-income countries, there is a paucity …