Type-2-cell-mediated immunity, rich in eosinophils, basophils, mast cells, CD4+ T helper 2
(Th2) cells, and type 2 innate lymphoid cells (ILC2s), protects the host from helminth …

Tremendous progress in the last few years has been made to explain how seemingly
harmless environmental proteins from different origins can induce potent Th2‐biased …

The physiological functions of mast cells remain largely an enigma. In the context of barrier
damage, mast cells are integrated in type 2 immunity and, together with immunoglobulin E …

Skin barrier structure and function is essential to human health. Hitherto unrecognized
functions of epidermal keratinocytes show that the skin plays an important role in adapting …

The relentless pursuit of effective strategies against skin aging has led to significant interest
in the role of bioactive factors, particularly secondary metabolites from natural sources. The …

Preparing a single cell suspension is a critical step in any solid tissue flow cytometry
experiment. Tissue dissection, enzymatic digestion, and mechanical dissociation are three …

Since mite allergens are the most relevant inducers of allergic diseases worldwide, resulting
in significant morbidity and increased burden on health services, the International …

Allergic diseases are an immune disorder reacting to certain type of allergen (s).
Remarkably only a small number of proteins of the plant and animal proteome act as …

CD4 T-helper cell type 2 (Th2) cells mediate host defense against extracellular parasites,
like helminths. However, Th2 cells also play a pivotal role in the onset and progression of …

Precision allergy molecular diagnostic applications (PAMD@) is increasingly entering
routine care. Currently, more than 130 allergenic molecules from more than 50 allergy …