▪ Abstract Bacterial lipopolysaccharides (LPS) typically consist of a hydrophobic domain
known as lipid A (or endotoxin), a nonrepeating “core” oligosaccharide, and a distal …

Exposures to bioaerosols in the occupational environment are associated with a wide range
of health effects with major public health impact, including infectious diseases, acute toxic …

Background Never smokers comprise a substantial proportion of patients with COPD. Their
characteristics and possible risk factors in this population are not yet well defined. Methods …

As the classic mineral dust-induced pneumoconioses decrease in frequency because of the
control of exposure, obstructive airway diseases have emerged as the most prevalent …

The sole human cathelicidin peptide, LL-37, has been demonstrated to protect animals
against endotoxemia/sepsis. Low, physiological concentrations of LL-37 (≤ 1 μg/ml) were …

Background Several recent studies have shown that growing up on a farm confers
significant protection against the development of atopy. These findings point particularly …

Background: Although research has shown that early life exposure to household endotoxin
protects against development of allergies, studies are less clear on the relationship between …

Lipopolysaccharide (LPS), a major proinflammatory glycolipid component of the gram-
negative bacterial cell wall, is one of the agents ubiquitously present as contaminant on …

Toxic gases, vapors, and particles are emitted from concentrated animal feeding operations
(CAFOs) into the general environment. These include ammonia, hydrogen sulfide, carbon …

We examined endotoxin exposure and wheezing episodes during the first year of life in a
birth cohort of 499 infants with one or both parents having a history of asthma or allergy. We …