Immunological roads diverged: map** tuberculosis outcomes in mice
The journey from phenotypic observation to causal genetic mechanism is a long and
challenging road. For pathogens like Mycobacterium tuberculosis (Mtb), which causes …
challenging road. For pathogens like Mycobacterium tuberculosis (Mtb), which causes …
Nucleoid‐associated proteins of mycobacteria come with a distinctive flavor
M Santoshi, P Tare, V Nagaraja - Molecular Microbiology, 2024 - Wiley Online Library
In every bacterium, nucleoid‐associated proteins (NAPs) play crucial roles in chromosome
organization, replication, repair, gene expression, and other DNA transactions. Their central …
organization, replication, repair, gene expression, and other DNA transactions. Their central …
Preclinical murine models for the testing of antimicrobials against Mycobacterium abscessus pulmonary infections: Current practices and recommendations
Mycobacterium abscessus, a rapidly growing nontuberculous mycobacterium, is
increasingly recognized as an important pathogen of the human lung, disproportionally …
increasingly recognized as an important pathogen of the human lung, disproportionally …
Mycobacterium tuberculosis FtsB and PerM interact via a C-terminal helix in FtsB to modulate cell division
JR Ferreira, R Xu, Z Hensel - bioRxiv, 2024 - biorxiv.org
Latent infection by Mycobacterium tuberculosis (Mtb) impedes effective tuberculosis therapy
and eradication. The protein PerM is essential for chronic Mtb infections in mice and acts via …
and eradication. The protein PerM is essential for chronic Mtb infections in mice and acts via …
Genetic Analysis of Mycobacterium tuberculosis Response to Stressors During Infection
K Dinshaw - 2024 - search.proquest.com
Mycobacterium tuberculosis (Mtb) is a bacterial pathogen that establishes a pulmonary
infection in the lung, and a quarter of the world's population is estimated to be latently …
infection in the lung, and a quarter of the world's population is estimated to be latently …
Evolution of targets at the host-pathogen interface
C Beaudoin - 2024 - repository.cam.ac.uk
Using comparative genomics, I investigate the protein-coding potential of globally-
distributed Mtb strains. Previous reports had suggested that the pan-genome (or all unique …
distributed Mtb strains. Previous reports had suggested that the pan-genome (or all unique …
Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered Using DNA-Encoded Chemical Library Screening
DNA-encoded chemical library (DEL) technology provides a time-and cost-efficient method
to simultaneously screen billions of compounds for their affinity to a protein target of interest …
to simultaneously screen billions of compounds for their affinity to a protein target of interest …