2016 updated EULAR evidence-based recommendations for the management of gout
Background New drugs and new evidence concerning the use of established treatments
have become available since the publication of the first European League Against …
have become available since the publication of the first European League Against …
Uric acid and cardiovascular risk
This review summarizes relevant studies concerning uric acid and possible links to
hypertension, renal disease, and cardiovascular disease. Whether uric acid is an …
hypertension, renal disease, and cardiovascular disease. Whether uric acid is an …
[HTML][HTML] Uric acid, hyperuricemia and vascular diseases
Uric acid is the product of purine metabolism. It is known that hyperuricemia, defined as high
levels of blood uric acid, is the major etiological factor of gout. A number of epidemiological …
levels of blood uric acid, is the major etiological factor of gout. A number of epidemiological …
[PDF][PDF] Is it time to revise the normal range of serum uric acid levels?
G Desideri, G Castaldo, A Lombardi… - European Review for …, 2014 - europeanreview.org
The actual reference range of serum uric acid has been assessed according to its variations
among healthy individuals. ie those without clinical evidence of gout. By this approach …
among healthy individuals. ie those without clinical evidence of gout. By this approach …
[HTML][HTML] The relationships among hyperuricemia, endothelial dysfunction, and cardiovascular diseases: molecular mechanisms and clinical implications
P Puddu, GM Puddu, E Cravero, L Vizioli, A Muscari - Journal of cardiology, 2012 - Elsevier
Uric acid is the end product of purine metabolism. Its immediate precursor, xanthine, is
converted to uric acid by an enzymatic reaction involving xanthine oxidoreductase. Uric acid …
converted to uric acid by an enzymatic reaction involving xanthine oxidoreductase. Uric acid …
Expert consensus for the diagnosis and treatment of patient with hyperuricemia and high cardiovascular risk
The definition of hyperuricemia (HU) varies widely in different studies, which makes the
epidemiological reports somewhat inconsistent. HU remains the culprit of the pathogenesis …
epidemiological reports somewhat inconsistent. HU remains the culprit of the pathogenesis …
The paradoxical relationship between serum uric acid and cardiovascular disease
Uric acid (urate), an organic compound comprised of carbon, nitrogen, oxygen and
hydrogen, is the final oxidation product of purine catabolism in humans, higher primates and …
hydrogen, is the final oxidation product of purine catabolism in humans, higher primates and …
Uric acid and incident dementia over 12 years of follow-up: a population-based cohort study
A Latourte, A Soumaré, T Bardin… - Annals of the …, 2018 - ard.bmj.com
Objectives In patients with gout, maintaining too low serum uric acid (SUA) level with urate-
lowering therapy is a concern because uric acid is thought to be neuroprotective. However …
lowering therapy is a concern because uric acid is thought to be neuroprotective. However …
Sex differences in cerebral small vessel disease: a systematic review and meta-analysis
L Jiménez-Sánchez, OKL Hamilton, U Clancy… - Frontiers in …, 2021 - frontiersin.org
Background: Cerebral small vessel disease (SVD) is a common cause of stroke, mild
cognitive impairment, dementia and physical impairments. Differences in SVD incidence or …
cognitive impairment, dementia and physical impairments. Differences in SVD incidence or …
Cerebral fructose metabolism as a potential mechanism driving Alzheimer's disease
The loss of cognitive function in Alzheimer's disease is pathologically linked with
neurofibrillary tangles, amyloid deposition, and loss of neuronal communication. Cerebral …
neurofibrillary tangles, amyloid deposition, and loss of neuronal communication. Cerebral …