Red blood cell distribution width: a simple parameter with multiple clinical applications
The red blood cell distribution width (RDW) is a simple and inexpensive parameter, which
reflects the degree of heterogeneity of erythrocyte volume (conventionally known as …
reflects the degree of heterogeneity of erythrocyte volume (conventionally known as …
[HTML][HTML] Animal models of atherosclerosis
An ideal animal model of atherosclerosis resembles human anatomy and pathophysiology
and has the potential to be used in medical and pharmaceutical research to obtain results …
and has the potential to be used in medical and pharmaceutical research to obtain results …
[HTML][HTML] Intraplaque hemorrhage and progression of coronary atheroma
FD Kolodgie, HK Gold, AP Burke… - … England Journal of …, 2003 - Mass Medical Soc
Background Intraplaque hemorrhage is common in advanced coronary atherosclerotic
lesions. The relation between hemorrhage and the vulnerability of plaque to disruption may …
lesions. The relation between hemorrhage and the vulnerability of plaque to disruption may …
Atherosclerotic plaque progression and vulnerability to rupture: angiogenesis as a source of intraplaque hemorrhage
R Virmani, FD Kolodgie, AP Burke, AV Finn… - … , and vascular biology, 2005 - Am Heart Assoc
Observational studies of necrotic core progression identify intraplaque hemorrhage as a
critical factor in atherosclerotic plaque growth and destabilization. The rapid accumulation of …
critical factor in atherosclerotic plaque growth and destabilization. The rapid accumulation of …
Macrophage subsets in atherosclerosis
G Chinetti-Gbaguidi, S Colin, B Staels - Nature Reviews Cardiology, 2015 - nature.com
Macrophage accumulation within the vascular wall is a hallmark of atherosclerosis. In
atherosclerotic lesions, macrophages respond to various environmental stimuli, such as …
atherosclerotic lesions, macrophages respond to various environmental stimuli, such as …
Atherosclerosis, platelets and thrombosis in acute ischaemic heart disease
L Badimon, T Padró, G Vilahur - European Heart Journal: Acute …, 2012 - academic.oup.com
Atherosclerosis is the underlying reason for nearly all causes of coronary artery disease and
peripheral arterial disease and many cases of stroke. Atherosclerosis is a systemic …
peripheral arterial disease and many cases of stroke. Atherosclerosis is a systemic …
Immune cell profiling in atherosclerosis: role in research and precision medicine
Inflammation is intimately involved at all stages of atherosclerosis and remains a substantial
residual cardiovascular risk factor in optimally treated patients. The proof of concept that …
residual cardiovascular risk factor in optimally treated patients. The proof of concept that …
A cell-autonomous role for border-associated macrophages in ApoE4 neurovascular dysfunction and susceptibility to white matter injury
Abstract Apolipoprotein E4 (ApoE4), the strongest genetic risk factor for sporadic Alzheimer's
disease, is also a risk factor for microvascular pathologies leading to cognitive impairment …
disease, is also a risk factor for microvascular pathologies leading to cognitive impairment …
Plaque neovascularization is increased in ruptured atherosclerotic lesions of human aorta: implications for plaque vulnerability
PR Moreno, KR Purushothaman, V Fuster… - Circulation, 2004 - Am Heart Assoc
Background—Growth of atherosclerotic plaques is accompanied by neovascularization from
vasa vasorum microvessels extending through the tunica media into the base of the plaque …
vasa vasorum microvessels extending through the tunica media into the base of the plaque …
Neovascularization in human atherosclerosis
PR Moreno, KR Purushothaman, M Sirol, AP Levy… - Circulation, 2006 - Am Heart Assoc
Coronary neovascularization may also accompany the early process of vessel wall
remodeling, as observed in hypercholesterolemic swine. 16 In this animal model …
remodeling, as observed in hypercholesterolemic swine. 16 In this animal model …