Both the cerebellum and the basal ganglia are known for their roles in motor control and
motivated behavior. These two systems have been classically considered as independent …

Schizophrenia (SZ) is a complex neuropsychiatric disorder associated with severe cognitive
dysfunction. Although research has mainly focused on forebrain abnormalities, emerging …

Abstract A general psychopathology ('p') factor captures shared variation across mental
disorders. One hypothesis is that poor executive function (EF) contributes to p. Although EF …

Psychiatric disorders share neurobiology and frequently co-occur. This neurobiological and
clinical overlap highlights opportunities for transdiagnostic treatments. In this study, we used …

This paper proposes a model for developmental psychopathology that is informed by recent
research suggestive of a single model of mental health disorder (the p factor) and seeks to …

Our understanding of cerebellar involvement in brain disorders has evolved from motor
processing to high-level cognitive and affective processing. Recent neuroscience progress …

Although cerebellar alterations have been implicated in stress symptoms, the exact
contribution of the cerebellum to stress symptoms remains to be elucidated. Here, we …

Childhood psychiatric symptoms are often diffuse but can coalesce into discrete mental
illnesses during late adolescence. We leveraged polygenic scores (PGSs) to parse genomic …

Background Adolescence is a key period for brain development and the emergence of
psychopathology. The Adolescent Brain Cognitive Development (ABCD) study was created …

This systematic review synthesizes evidence from research investigating the biological
correlates of latent transdiagnostic dimensions of psychopathology (eg, the p-factor …