Cerebellar contributions to the basal ganglia influence motor coordination, reward processing, and movement vigor
Both the cerebellum and the basal ganglia are known for their roles in motor control and
motivated behavior. These two systems have been classically considered as independent …
motivated behavior. These two systems have been classically considered as independent …
[HTML][HTML] Transdiagnostic biomarkers of mental illness across the lifespan: a systematic review examining the genetic and neural correlates of latent transdiagnostic …
This systematic review synthesizes evidence from research investigating the biological
correlates of latent transdiagnostic dimensions of psychopathology (eg, the p-factor …
correlates of latent transdiagnostic dimensions of psychopathology (eg, the p-factor …
A transdiagnostic network for psychiatric illness derived from atrophy and lesions
Psychiatric disorders share neurobiology and frequently co-occur. This neurobiological and
clinical overlap highlights opportunities for transdiagnostic treatments. In this study, we used …
clinical overlap highlights opportunities for transdiagnostic treatments. In this study, we used …
[HTML][HTML] Is executive dysfunction a risk marker or consequence of psychopathology? A test of executive function as a prospective predictor and outcome of general …
Abstract A general psychopathology ('p') factor captures shared variation across mental
disorders. One hypothesis is that poor executive function (EF) contributes to p. Although EF …
disorders. One hypothesis is that poor executive function (EF) contributes to p. Although EF …
Culture and psychopathology: An attempt at reconsidering the role of social learning
This paper proposes a model for developmental psychopathology that is informed by recent
research suggestive of a single model of mental health disorder (the p factor) and seeks to …
research suggestive of a single model of mental health disorder (the p factor) and seeks to …
Genetic patterning for child psychopathology is distinct from that for adults and implicates fetal cerebellar development
Childhood psychiatric symptoms are often diffuse but can coalesce into discrete mental
illnesses during late adolescence. We leveraged polygenic scores (PGSs) to parse genomic …
illnesses during late adolescence. We leveraged polygenic scores (PGSs) to parse genomic …
Pervasively thinner neocortex as a transdiagnostic feature of general psychopathology
Objective: Neuroimaging research has revealed that structural brain alterations are common
across broad diagnostic families of disorders rather than specific to a single psychiatric …
across broad diagnostic families of disorders rather than specific to a single psychiatric …
VTA-projecting cerebellar neurons mediate stress-dependent depression-like behaviors
Although cerebellar alterations have been implicated in stress symptoms, the exact
contribution of the cerebellum to stress symptoms remains to be elucidated. Here, we …
contribution of the cerebellum to stress symptoms remains to be elucidated. Here, we …
Compression of cerebellar functional gradients in schizophrenia
Our understanding of cerebellar involvement in brain disorders has evolved from motor
processing to high-level cognitive and affective processing. Recent neuroscience progress …
processing to high-level cognitive and affective processing. Recent neuroscience progress …
Neurobiological, familial and genetic risk factors for dimensional psychopathology in the Adolescent Brain Cognitive Development study
Background Adolescence is a key period for brain development and the emergence of
psychopathology. The Adolescent Brain Cognitive Development (ABCD) study was created …
psychopathology. The Adolescent Brain Cognitive Development (ABCD) study was created …