The development of functional non-viral vectors for gene delivery

S Patil, YG Gao, X Lin, Y Li, K Dang, Y Tian… - International journal of …, 2019 - mdpi.com
Gene therapy is manipulation in/of gene expression in specific cells/tissue to treat diseases.
This manipulation is carried out by introducing exogenous nucleic acids, such as DNA or …

Organelle-targeting metal complexes: From molecular design to bio-applications

K Qiu, Y Chen, TW Rees, L Ji, H Chao - Coordination Chemistry Reviews, 2019 - Elsevier
Cellular organelles, such the cytomembrane, lysosome, mitochondrion, Golgi apparatus, the
endoplasmic reticulum, and nucleus, play important roles in the normal function of cells …

Biochar effectively inhibits the horizontal transfer of antibiotic resistance genes via transformation

J Fang, L **, Q Meng, S Shan, D Wang… - Journal of Hazardous …, 2022 - Elsevier
The rapid spread of antibiotic resistance genes (ARGs) has posed a risk to human health.
Here, the effects of biochar (BC) on the horizontal transfer of ARG-carrying plasmids to …

Interactions of copper complexes with nucleic acids

A Erxleben - Coordination Chemistry Reviews, 2018 - Elsevier
Covalent or non-covalent interactions with DNA are the basis for many potential biomedical
applications of copper complexes, ranging from DNA structural probes and footprinting …

A long lifetime iridium (III) complex as a sensitive luminescent probe for bisulfite detection in living zebrafish

JB Liu, C Yang, CN Ko, K Vellaisamy, B Yang… - Sensors and Actuators B …, 2017 - Elsevier
A long-lived iridium (III) complex probe Ir_1 for bisulfite detection has been synthesized. The
iridium (III) complex probe Ir_1, containing double aldehyde groups in the N^ N donor …

Phosphorescent iridium (III) complexes for anticancer applications

R Guan, L **e, L Ji, H Chao - European Journal of Inorganic …, 2020 - Wiley Online Library
Great attention has been bestowed upon iridium (III) complexes as anticancer agents in
recent years, and a variety of them, in particular, are luminescent. The phosphorescence of …

Water soluble transition metal [Ni (II), Cu (II) and Zn (II)] complexes of N-phthaloylglycinate bis (1, 2-diaminocyclohexane). DNA binding, pBR322 cleavage and …

S Khursheed, HR Siddique, S Tabassum… - Dalton …, 2022 - pubs.rsc.org
To validate the effect of metal ions in analogous ligand scaffolds on DNA binding and
cytotoxic response, we have synthesized a series of water-soluble ionic N …

Synthesis, Characterization, and Anticancer Activity of New Metal Complexes Derived from 2‐Hydroxy‐3‐(hydroxyimino)‐4‐oxopentan‐2‐ylidene) benzohydrazide

AS El-Tabl, M Mohamed Abd El-Waheed… - Bioinorganic …, 2015 - Wiley Online Library
Novel metal (II) complexes derived from 2‐hydroxy‐N′‐((Z)‐3‐(hydroxyimino)‐4‐
oxopentan‐2‐ylidene) benzohydrazide ligand (H2L) were synthesized and characterized by …

Soil minerals and organic matters affect ARGs transformation by changing the morphology of plasmid and bacterial responses

H Shi, X Hu, J Zhang, W Li, J Xu, B Hu, L Ma… - Journal of Hazardous …, 2023 - Elsevier
Soil environment is a vital place for the occurrence and spread of antibiotic resistant bacteria
(ARB) and antibiotic resistance genes (ARGs). Extracellular DNA-mediated transformation is …

Nanopore-based single-molecule investigation of cation effect on the i-motif structure

Z Wang, R Cui, L Liu, L Li, Z Li, X Liu… - The Journal of Physical …, 2024 - ACS Publications
The i-motif, a secondary structure of a four-helix formed by cytosine-rich DNA (i-DNA)
through C–C+ base pairing, is prevalent in human telomeres and promoters. This structure …