Thyroid and COVID-19: a review on pathophysiological, clinical and organizational aspects

G Lisco, A De Tullio, E Jirillo, VA Giagulli… - Journal of …, 2021 - Springer
Background Thyroid dysfunction has been observed in patients with COVID-19, and
endocrinologists are requested to understand this clinical issue. Pandemic-related …

[HTML][HTML] Viral proteases as therapeutic targets

T Majerová, J Konvalinka - Molecular aspects of medicine, 2022 - Elsevier
Some medically important viruses―including retroviruses, flaviviruses, coronaviruses, and
herpesviruses―code for a protease, which is indispensable for viral maturation and …

[HTML][HTML] COVID-19 signalome: Potential therapeutic interventions

K Lundstrom, A Hromić-Jahjefendić, E Bilajac… - Cellular signalling, 2023 - Elsevier
The COVID-19 pandemic has triggered intensive research and development of drugs and
vaccines against SARS-CoV-2 during the last two years. The major success was especially …

[HTML][HTML] Metallo-antiviral aspirants: answer to the upcoming virus outbreak

R Mehrotra, SN Shukla, P Gaur - European Journal of Medicinal Chemistry …, 2023 - Elsevier
In light of the current SARS-CoV-2 outbreak, about one million research papers (articles,
reviews, communications, etc.) were published in the last one and a half years. It was also …

A review on drug repurposing in COVID-19: from antiviral drugs to herbal alternatives

A Sezer, M Halilović-Alihodžić, AR Vanwieren… - Journal of Genetic …, 2022 - Springer
Background COVID-19 is an illness caused by severe acute respiratory syndrome
coronavirus 2. Due to its rapid spread, in March 2020 the World Health Organization (WHO) …

The impact of SARS-CoV-2 treatment on the cardiovascular system: An updated review

MA Akkaif, A Sha'aban, A Cesaro, AAS Jaber… - …, 2022 - Springer
Abstract The coronavirus disease-2019 (COVID-19) pandemic has become a major global
health problem. COVID-19 is caused by severe acute respiratory syndrome coronavirus-2 …

BRET-based self-cleaving biosensors for SARS-CoV-2 3CLpro inhibitor discovery

N Hou, C Peng, L Zhang, Y Zhu, Q Hu - Microbiology Spectrum, 2022 - journals.asm.org
ABSTRACT The 3C-like protease (3CLpro) of SARS-CoV-2 is an attractive drug target for
develo** antivirals against SARS-CoV-2. A few small molecule inhibitors of 3CLpro are in …

Targeting COVID-19 (SARS-CoV-2) main protease through phytochemicals of Albizia lebbeck: molecular docking, molecular dynamics simulation, MM–PBSA free …

N Nalban, M Wanjari, R Kolhe, M Tamboli… - Journal of Proteins and …, 2024 - Springer
The unforeseen occurrence of the new coronavirus disease (COVID-19) has affected eight
million people worldwide. There is an urgent need to develop new drugs to combat the …