Chronic kidney disease (CKD) is the leading complication in type 2 diabetes (T2D) and
current therapies that limit CKD progression and the development of cardiovascular disease …

The etiology of hypertension involves complex interactions among genetic, environmental,
and pathophysiologic factors that influence many regulatory systems. Hypertension is …

Aldosterone is a mineralocorticoid hormone that controls body fluid and electrolyte balance.
Excess aldosterone is associated with cardiovascular and metabolic diseases. Inflammation …

Mineralocorticoid receptor (MR) activation in the heart and vessels leads to pathological
effects, such as excessive extracellular matrix accumulation, oxidative stress, and sustained …

Among all physiologic functions of nitric oxide (NO) known so far, NO-dependent regulation
of vascular tone is one of the most important. Under physiological conditions vascular NO is …

Aldosterone excess aggravates endothelial dysfunction in diabetes and hypertension by
promoting the increased generation of reactive oxygen species, inflammation, and insulin …

The regulation of aldosterone secretion by leptin: implicati... : Current Opinion in
Nephrology and Hypertension The regulation of aldosterone secretion by leptin …

Vascular calcification resulting from hyperphosphatemia is a major determinant of mortality
in chronic kidney disease (CKD). Vascular calcification is driven by aldosterone-sensitive …

The progression of chronic kidney disease (CKD) cannot be completely inhibited. We first
explored factors contributing to CKD progression in patients with CKD in a prospective …

The aim of this study was to analyze the impact of circadian variation of blood pressure (BP)
in patients with chronic musculoskeletal pain (CPM). A further purpose was to study …