From QTL to gene: C. elegans facilitates discoveries of the genetic mechanisms underlying natural variation
Although many studies have examined quantitative trait variation across many species, only
a small number of genes and thereby molecular mechanisms have been discovered …
a small number of genes and thereby molecular mechanisms have been discovered …
Genetic approaches for increasing fitness in endangered species
The global rate of wildlife extinctions is accelerating, and the persistence of many species
requires conservation breeding programs. A central paradigm of these programs is to …
requires conservation breeding programs. A central paradigm of these programs is to …
Genome-wide map** of regulatory variants for temperature-and salinity-adaptive genes reveals genetic basis of genotype-by-environment interaction in …
K Zhang, Q Yang, M Du, Z Zhang, W Wang… - Environmental …, 2023 - Elsevier
Regulatory variants in gene expression serve as bridges linking genetic variation and
phenotypic plasticity. Environmental conditions typically influence the effects of regulatory …
phenotypic plasticity. Environmental conditions typically influence the effects of regulatory …
Detecting selection with a genetic cross
HB Fraser - Proceedings of the National Academy of …, 2020 - National Acad Sciences
Distinguishing which traits have evolved under natural selection, as opposed to neutral
evolution, is a major goal of evolutionary biology. Several tests have been proposed to …
evolution, is a major goal of evolutionary biology. Several tests have been proposed to …
Gene expression variation underlying tissue-specific responses to copper stress in Drosophila melanogaster
Copper is one of a handful of biologically necessary heavy metals that is also a common
environmental pollutant. Under normal conditions, copper ions are required for many key …
environmental pollutant. Under normal conditions, copper ions are required for many key …
WormQTL2: an interactive platform for systems genetics in Caenorhabditis elegans
Quantitative genetics provides the tools for linking polymorphic loci to trait variation. Linkage
analysis of gene expression is an established and widely applied method, leading to the …
analysis of gene expression is an established and widely applied method, leading to the …
Heat Stress Reduces the Susceptibility of Caenorhabditis elegans to Orsay Virus Infection
The nematode Caenorhabditis elegans has been a versatile model for understanding the
molecular responses to abiotic stress and pathogens. In particular, the response to heat …
molecular responses to abiotic stress and pathogens. In particular, the response to heat …
Life history in Caenorhabditis elegans: from molecular genetics to evolutionary ecology
Life history is defined by traits that reflect key components of fitness, especially those relating
to reproduction and survival. Research in life history seeks to unravel the relationships …
to reproduction and survival. Research in life history seeks to unravel the relationships …
The genetics of gene expression in a Caenorhabditis elegans multiparental recombinant inbred line population
Studying genetic variation of gene expression provides a powerful way to unravel the
molecular components underlying complex traits. Expression quantitative trait locus (eQTL) …
molecular components underlying complex traits. Expression quantitative trait locus (eQTL) …
The genetic architecture underlying body-size traits plasticity over different temperatures and developmental stages in Caenorhabditis elegans
Most ectotherms obey the temperature-size rule, meaning they grow larger in a colder
environment. This raises the question of how the interplay between genes and temperature …
environment. This raises the question of how the interplay between genes and temperature …