Small molecule therapeutics represent the majority of the FDA-approved drugs. Yet, many
attractive targets are poorly tractable by small molecules, generating a need for new …

Increased pressure on upstream processes to maximize productivity has been crowned with
great success, although at the cost of shifting the bottleneck to purification. As drivers were …

Native forms of therapeutic monoclonal antibodies (mAbs) coexist with various acidic and
basic charge variants throughout process development and into drug product formulation …

Among bacterial expression system, Escherichia coli was the popular and widely used
expression host due to its high rate expression trait. However, overexpression of …

PEGylation of therapeutic proteins has long been recognized as a safe and effective
approach to enhance pharmacokinetic properties of proteins by increasing the in-vivo half …

It is now over 25 years since the term proteomics (analysis of the entire protein complement
of a cell, tissue, or organism under a specific, defined set of conditions) was originally …

The exclusive properties of monolithic supports enable fast mass transfer, high porosity, low
back pressure, easy preparation process and miniaturisation, and the availability of different …

Peptides and proteins have been known for more than a century, but was only when du
Vigneaud published the first synthesis of oxytocin, that the research on bioactive peptides …

While epoxy resins exhibit excellent mechanical and insulating properties as well as
excellent stability against heat and chemicals, epoxy adhesives also have drawbacks such …

The present state of the art of studying whey is considered. The processes and methods of
whey processing (thermal, chemical, physicochemical, biotechnological, and …