Neuromyelitis optica (NMO) is an autoimmune, demyelinating disorder of the central
nervous system (CNS) with typical clinical manifestations of optic neuritis and acute …

The soluble membrane attack complex (sMAC, aka, sC5b-9 or TCC) is generated on
activation of complement and contains the complement proteins C5b, C6, C7, C8, C9 …

The term neuromyelitis optica spectrum disorder (NMOSD) describes a group of clinical-MRI
syndromes characterized by longitudinally extensive transverse myelitis, optic neuritis …

The Neuromyelitis Optica Spectrum Disorders (NMOSD) constitute a spectrum of rare
autoimmune diseases of the central nervous system characterized by episodes of transverse …

Complement is thought to play a pivotal role in neuromyelitis optica (NMO) pathogenesis.
Anaphylatoxins (C3a, C4a, and C5a), produced in complement activation, have …

The role of complement has been demonstrated in experimental models of neuromyelitis
optica (NMO), however, only few studies have analysed complement components …

Background: Multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD)
are autoimmune inflammatory demyelinating diseases of the central nervous system …

Neuromyelitis optica (NMO) and multiple sclerosis (MS) are two of the autoimmune
inflammatory demyelinating diseases in the central nervous system. Complement is thought …

Objectives Systemic vasculitis is a heterogenous group of autoimmune diseases
characterized by enhanced cardiovascular mortality. Endothelial dysfunction is associated …

Introduction With the advent of targeted drugs, a correct identification of patients with
neuromyelitis optica spectrum disorders (NMOSD) is fundamental. Moreover, to assess …