The cellular senescence definition comes to the fact of cells irreversible proliferation
disability. Besides the cell cycle arrest, senescent cells go through some morphological …

Significance: Severe life stress (SLS), as opposed to trivial everyday stress, is defined as a
serious psychosocial event with the potential of causing an impacting psychological …

There is increasing interest in discovering mechanisms that mediate the effects of childhood
stress on late-life disease morbidity and mortality. Previous studies have suggested one …

Background: Telomeres shorten with each cell division and are essential for chromosomal
stability. Short telomeres in surrogate tissues (eg, blood cells) are associated with increased …

Cancer is considered the most important clinical, social and economic issue regarding
cause‑specific disability‑adjusted life years among all human pathologies. Exogenous …

Context Telomeres are essential to preserve the integrity of the genome. Critically short
telomeres lead to replicative cell senescence and chromosomal instability and may thereby …

Background Telomeres play a key role in the maintenance of chromosome integrity and
stability, and telomere shortening is involved in initiation and progression of malignancies. A …

Telomeres are nucleoprotein structures, located at the ends of chromosomes and are
subject to shortening at each cycle of cell division. They prevent chromosomal ends from …

Background: Leukocyte telomere length is associated with diseases of aging, but there is
limited knowledge of diet and lifestyle determinants. Objective: The objective was to …

Telomere biology disorders are a complex set of illnesses defined by the presence of very
short telomeres. Individuals with classic dyskeratosis congenita have the most severe …