Marek's disease in chickens: a review with focus on immunology

N Boodhoo, A Gurung, S Sharif, S Behboudi - Veterinary research, 2016 - Springer
Abstract Marek's disease (MD), caused by Marek's disease virus (MDV), is a commercially
important neoplastic disease of poultry which is only controlled by mass vaccination …

Specific and nonspecific immune responses to Marek's disease virus

KA Schat, Z **ng - Developmental & Comparative Immunology, 2000 - Elsevier
Marek's disease (MD) virus (MDV) has provided an important model to study immune
responses against a lymphoma-inducing herpesvirus in its natural host. Infection in chickens …

Pathogenesis of Marek's disease virus infection

BW Calnek - Marek's disease, 2001 - Springer
The term pathogenesis is most simply defined as the development of disease. Many
uncomplicated infectious diseases proceed in a direct fashion from infection to a specific …

Differential cytokine responses following Marek's disease virus infection of chickens differing in resistance to Marek's disease

P Kaiser, G Underwood, F Davison - Journal of virology, 2003 - Am Soc Microbiol
The production of cytokine mRNAs, in addition to viral DNA, was quantified by real-time
quantitative reverse transcription-PCR (RT-PCR)(cytokines) or PCR (virus) in splenocytes …

Comparative analysis of Marek's disease virus (MDV) glycoprotein-, lytic antigen pp38-and transformation antigen Meq-encoding genes: association of meq mutations …

CE Shamblin, N Greene, V Arumugaswami… - Veterinary …, 2004 - Elsevier
Marek's disease (MD) is a highly contagious lymphoproliferative and demyelinating disorder
of chickens. MD is caused by Marek's disease virus (MDV), a cell-associated, acute …

Structures of an MHC class I molecule from B21 chickens illustrate promiscuous peptide binding

M Koch, S Camp, T Collen, D Avila, J Salomonsen… - Immunity, 2007 - cell.com
Little is known about the structure of major histocompatibility complex (MHC) molecules
outside of mammals. Only one class I molecule in the chicken MHC is highly expressed …

Neoplastic diseases

V Nair, I Gimeno, J Dunn, G Zavala… - Diseases of …, 2020 - Wiley Online Library
This chapter deals primarily with the three most economically important virus‐induced
transmissible neoplastic diseases of poultry, namely: the herpesvirus‐induced Marek's …

An anti-tumor vaccine against Marek's disease virus induces differential activation and memory response of γδ T cells and CD8 T cells in chickens

X Hao, S Li, J Li, Y Yang, A Qin, S Shang - Frontiers in Immunology, 2021 - frontiersin.org
Marek's disease virus (MDV) is a highly oncogenic alphaherpesvirus that causes deadly T-
cell lymphomas and serves as a natural virus-induced tumor model in chickens. The most …

Differential virus-specific IFN-gamma producing T cell responses to marek's disease virus in chickens with B19 and B21 MHC haplotypes

N Boodhoo, S Behboudi - Frontiers in Immunology, 2022 - frontiersin.org
Marek's disease virus (MDV), the etiologic agent for Marek's disease (MD), causes a deadly
lymphoproliferative disease in chickens. Causes of the well-documented association …

Pathogenesis of Marek's disease (MD) and possible mechanisms of immunity induced by MD vaccine

T MORIMURA, K OHASHI, C SUGIMOTO… - Journal of veterinary …, 1998 - jstage.jst.go.jp
Marek's disease (MD) is a lymphoproliferative disease of chicken, which is characterized by
malignant T cell-lymphoma formation. This disease can be effectively prevented by …