For more than one century, brain processing was mainly thought in a localizationist
framework, in which one given function was underpinned by a discrete, isolated cortical …

Stroke has long been regarded as focal disease with circumscribed damage leading to
neurological deficits. However, advances in methods for assessing the human brain and in …

Drug addiction is a public health crisis for which new treatments are urgently needed. In rare
cases, regional brain damage can lead to addiction remission. These cases may be used to …

The brain is constituted of multiple networks of functionally correlated brain areas, out of
which the default-mode network (DMN) is the largest. Most existing research into the DMN …

Behavioural deficits in stroke reflect both structural damage at the site of injury, and
widespread network dysfunction caused by structural, functional, and metabolic …

Creative ideas likely result from searching and combining semantic memory knowledge, yet
the mechanisms acting on memory to yield creative ideas remain unclear. Here, we …

Brain lesions do not just disable but also disconnect brain areas, which once deprived of
their input or output, can no longer subserve behaviour and cognition. The role of white …

Stroke significantly impacts the quality of life. However, the long-term cognitive evolution in
stroke is poorly predictable at the individual level. There is an urgent need to better predict …

Importance It is controversial whether epilepsy is a static or progressive disease. Evidence
of progressive gray matter loss in epilepsy would support early diagnosis, rapid treatment …

Clinicians and scientists alike have long sought to predict the course and severity of chronic
post-stroke cognitive and motor outcomes, as the ability to do so would inform treatment and …