Escherichia coli is one of the organisms of choice for the production of recombinant proteins.
Its use as a cell factory is well-established and it has become the most popular expression …

Antimicrobial peptides (AMPs) found in a wide range of animal, insect, and plant species are
host defense peptides forming an integral part of their innate immunity. Although the exact …

We report the de novo design of small (< 20 kDa) and highly soluble synthetic intrinsically
disordered proteins (SynIDPs) that confer solubility to a fusion partner with minimal effect on …

Tag-assisted protein purification is a method of choice for both academic researches and
large-scale industrial demands. Application of the purification tags in the protein production …

Protein expression is a critical process in diverse biological systems. For Escherichia coli, a
widely employed microbial host in industrial catalysis and healthcare, researchers often face …

In a biological system, the spatiotemporal arrangement of enzymes in a dense cellular
milieu, subcellular compartments, membrane-associated enzyme complexes on cell …

Membrane proteins are still heavily under-represented in the protein data bank (PDB),
owing to multiple bottlenecks. The typical low abundance of membrane proteins in their …

Expression of recombinant proteins in Escherichia coli (E. coli) remains the most popular
and cost-effective method for producing proteins in basic research and for pharmaceutical …

Biomolecular condensates are broadly implicated in both normal cellular regulation and
disease. Consequently, several chemical biology and optogenetic approaches have been …

Bacteriocins are a diverse group of ribosomally synthesised antimicrobial peptides/proteins
that play an important role in self-defence. They are widely used as bio-preservatives and …