Software and computational tools for LC-MS-based epilipidomics: Challenges and solutions
Lipids play a crucial role in cellular structure and functions, including cell signaling,
membrane plasticity, and trafficking. Alterations of the lipid composition in cells, tissues, or …
membrane plasticity, and trafficking. Alterations of the lipid composition in cells, tissues, or …
Phosphoinositides in autophagy: current roles and future insights
Today, the importance of autophagy in physiological processes and pathological conditions
is undeniable. Initially, autophagy merely was described as an evolutionarily conserved …
is undeniable. Initially, autophagy merely was described as an evolutionarily conserved …
Phospholipid removal for enhanced chemical exposomics in human plasma
K Sdougkou, H **e, S Papazian… - Environmental …, 2023 - ACS Publications
The challenge of chemical exposomics in human plasma is the 1000-fold concentration gap
between endogenous substances and environmental pollutants. Phospholipids are the …
between endogenous substances and environmental pollutants. Phospholipids are the …
A relative quantitative positive/negative ion switching method for untargeted lipidomics via high resolution LC-MS/MS from any biological source
SB Breitkopf, SJH Ricoult, M Yuan, Y Xu, DA Peake… - Metabolomics, 2017 - Springer
Introduction Advances in high-resolution mass spectrometry have created renewed interest
for studying global lipid biochemistry in disease and biological systems. Objectives Here, we …
for studying global lipid biochemistry in disease and biological systems. Objectives Here, we …
Flow cytometry has a significant impact on the cellular metabolome
The characterization of specialized cell subpopulations in a heterogeneous tissue is
essential for understanding organ function in health and disease. A popular method of cell …
essential for understanding organ function in health and disease. A popular method of cell …
Untargeted metabolomics and inflammatory markers profiling in children with Crohn's disease and ulcerative colitis—A preliminary study
U Daniluk, J Daniluk, R Kucharski… - Inflammatory Bowel …, 2019 - academic.oup.com
Background Metabolic profiling might be used to identify disease biomarkers. The aim of our
study was to determine the usefulness of untargeted metabolomics analysis to detect …
study was to determine the usefulness of untargeted metabolomics analysis to detect …
Comprehensive characterization of bovine milk lipids: Phospholipids, sphingolipids, glycolipids, and ceramides
A comprehensive survey on phospholipids (PLs), sphingolipids, glycolipids, and ceramides
(Cer) of bovine milk was conducted by liquid chromatography tandem-mass spectrometry. A …
(Cer) of bovine milk was conducted by liquid chromatography tandem-mass spectrometry. A …
Automated annotation of untargeted all-ion fragmentation LC–MS metabolomics data with MetaboAnnotatoR
Untargeted metabolomics and lipidomics LC–MS experiments produce complex datasets,
usually containing tens of thousands of features from thousands of metabolites whose …
usually containing tens of thousands of features from thousands of metabolites whose …
Knowledge-based metabolite annotation tool: CEU Mass Mediator
Abstract CEU Mass Mediator (CMM) is an on-line tool for aiding researchers when
performing metabolite annotation. Its database is comprised of 279,318 real compounds …
performing metabolite annotation. Its database is comprised of 279,318 real compounds …
Assessment of lemon juice adulteration by targeted screening using LC-UV-MS and untargeted screening using UHPLC-QTOF/MS with machine learning
The aim of this work was to develop an approach combining LC-MS-based metabolomics
and machine learning to distinguish between and predict authentic and adulterated lemon …
and machine learning to distinguish between and predict authentic and adulterated lemon …