Adherens junctions as molecular regulators of emergent tissue mechanics
Tissue and organ development during embryogenesis relies on the collective and
coordinated action of many cells. Recent studies have revealed that tissue material …
coordinated action of many cells. Recent studies have revealed that tissue material …
E-cadherin junctions as active mechanical integrators in tissue dynamics
During epithelial morphogenesis, E-cadherin adhesive junctions play an important part in
mechanically coupling the contractile cortices of cells together, thereby distributing the …
mechanically coupling the contractile cortices of cells together, thereby distributing the …
Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling
M Takeichi - Nature reviews Molecular cell biology, 2014 - nature.com
Epithelial cells display dynamic behaviours, such as rearrangement, movement and shape
changes, particularly during embryonic development and in equivalent processes in adults …
changes, particularly during embryonic development and in equivalent processes in adults …
New insights into the regulation and cellular functions of the ARP2/3 complex
JD Rotty, C Wu, JE Bear - Nature reviews Molecular cell biology, 2013 - nature.com
Abstract The actin-related protein 2/3 (ARP2/3) complex nucleates branched actin filament
networks, but requires nucleation promoting factors (NPFs) to stimulate this activity. NPFs …
networks, but requires nucleation promoting factors (NPFs) to stimulate this activity. NPFs …
Adherens junction: the ensemble of specialized cadherin clusters
SM Troyanovsky - Trends in cell biology, 2023 - cell.com
The cell–cell connections in adherens junctions (AJs) are mediated by transmembrane
receptors, type I cadherins (referred to here as cadherins). These cadherin-based …
receptors, type I cadherins (referred to here as cadherins). These cadherin-based …
Stress relaxation in epithelial monolayers is controlled by the actomyosin cortex
N Khalilgharibi, J Fouchard, N Asadipour, R Barrientos… - Nature physics, 2019 - nature.com
Epithelial monolayers are one-cell-thick tissue sheets that line most of the body surfaces,
separating internal and external environments. As part of their function, they must withstand …
separating internal and external environments. As part of their function, they must withstand …
Personalized immunotherapy against several neuronal and brain tumors
S Kuttruff-coqui, T Weinschenk, J Fritsche… - US Patent …, 2021 - Google Patents
2014-11-12 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
Mechanosensing and mechanotransduction at cell–cell junctions
K Duszyc, V Viasnoff - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Cell adhesion systems are defined by their ability to resist detachment force. Our
understanding of the biology of cell–cell adhesions has recently been transformed by the …
understanding of the biology of cell–cell adhesions has recently been transformed by the …
Contact inhibition (of proliferation) redux
AI McClatchey, AS Yap - Current opinion in cell biology, 2012 - Elsevier
It has long been appreciated that proliferation of many cells is inhibited by density, a
phenomenon that is often attributed to cell–cell contact. The basic properties of this …
phenomenon that is often attributed to cell–cell contact. The basic properties of this …
Cadherin-mediated cell-cell interactions in normal and cancer cells
NA Gloushankova, SN Rubtsova, IY Zhitnyak - Tissue barriers, 2017 - Taylor & Francis
Adherens junctions (AJs) are molecular complexes that mediate cell-cell adhesive
interactions and play pivotal roles in maintenance of tissue organization in adult organisms …
interactions and play pivotal roles in maintenance of tissue organization in adult organisms …