Endoplasmic reticulum stress in liver diseases
The endoplasmic reticulum (ER) is an intracellular organelle that fosters the correct folding
of linear polypeptides and proteins, a process tightly governed by the ER‐resident enzymes …
of linear polypeptides and proteins, a process tightly governed by the ER‐resident enzymes …
Saffron (Crocus sativus L.): A Source of Nutrients for Health and for the Treatment of Neuropsychiatric and Age-Related Diseases
A El Midaoui, I Ghzaiel, D Vervandier-Fasseur, M Ksila… - Nutrients, 2022 - mdpi.com
Saffron (Crocus sativus L.) is a medicinal plant, originally cultivated in the East and Middle
East, and later in some Mediterranean countries. Saffron is obtained from the stigmas of the …
East, and later in some Mediterranean countries. Saffron is obtained from the stigmas of the …
Polygonatum sibiricum polysaccharide prevents depression-like behaviors by reducing oxidative stress, inflammation, and cellular and synaptic damage
F Shen, Z Song, P **e, L Li, B Wang, D Peng… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance According to traditional Chinese medicine (TCM) theory
(Yi Xue Zheng Zhuan), the main factors associated with the pathogenesis of depression are …
(Yi Xue Zheng Zhuan), the main factors associated with the pathogenesis of depression are …
Anti-hepatocellular carcinoma biomolecules: molecular targets insights
This report explores the available curative molecules directed against hepatocellular
carcinoma (HCC). Limited efficiency as well as other drawbacks of existing molecules led to …
carcinoma (HCC). Limited efficiency as well as other drawbacks of existing molecules led to …
Multi-spectroscopic investigation, molecular docking and molecular dynamic simulation of competitive interactions between flavonoids (quercetin and rutin) and …
The main mechanism for drug-drug interaction is displacement reaction of ligands from their
protein binding sites. The aim of this study was to evaluate anticancer drug sorafenib …
protein binding sites. The aim of this study was to evaluate anticancer drug sorafenib …
Antioxidant and anticancer activities of chamomile (Matricaria recutita L.)
Objectives The present study aimed at determining the antioxidant activity, total phenols and
flavonoids and to evaluate the antiproliferative activity of ethanolic extract of Matricaria …
flavonoids and to evaluate the antiproliferative activity of ethanolic extract of Matricaria …
Saffron and its major ingredients' effect on colon cancer cells with mismatch repair deficiency and microsatellite instability
Background: Colorectal cancer (CRC) is one of the most common cancers worldwide. One
of its subtypes is associated with defective mismatch repair (dMMR) genes. Saffron has …
of its subtypes is associated with defective mismatch repair (dMMR) genes. Saffron has …
Safranal prevents liver cancer through inhibiting oxidative stress and alleviating inflammation
Despite all efforts, an effective and safe treatment for liver cancer remains elusive. Natural
products and their derived biomolecules are potential resources to mine for novel anti …
products and their derived biomolecules are potential resources to mine for novel anti …
Molecular mechanisms behind safranal's toxicity to HepG2 cells from dual omics
DR Nelson, AA Hrout, AS Alzahmi, A Chaiboonchoe… - Antioxidants, 2022 - mdpi.com
The spice saffron (Crocus sativus) has anticancer activity in several human tissues, but the
molecular mechanisms underlying its potential therapeutic effects are poorly understood …
molecular mechanisms underlying its potential therapeutic effects are poorly understood …
Role of plant-derived active constituents in cancer treatment and their mechanisms of action
Despite significant technological advancements in conventional therapies, cancer remains
one of the main causes of death worldwide. Although substantial progress has been made …
one of the main causes of death worldwide. Although substantial progress has been made …