Cytotoxicity of snake venom enzymatic toxins: phospholipase A2 and l-amino acid oxidase
The phospholipase A2 (PLA2) and l-amino acid oxidase (LAAO) are two major enzymes
found in the venoms from most snake species. These enzymes have been structurally and …
found in the venoms from most snake species. These enzymes have been structurally and …
Snake venom toxins: Potential anticancer therapeutics
Snake venom contains a cocktail of compounds dominated by proteins and peptides, which
make up the toxin. The toxin components of snake venom attack several targets in the …
make up the toxin. The toxin components of snake venom attack several targets in the …
Venom-gland transcriptome and venom proteome of the Malaysian king cobra (Ophiophagus hannah)
Abstract Background The king cobra (Ophiophagus hannah) is widely distributed throughout
many parts of Asia. This study aims to investigate the complexity of Malaysian Ophiophagus …
many parts of Asia. This study aims to investigate the complexity of Malaysian Ophiophagus …
Oxidative stress induced by Pollonein-LAAO, a new L-amino acid oxidase from Bothrops moojeni venom, prompts prostate tumor spheroid cell death and impairs the …
L Polloni, TR Costa, LP Morais, BC Borges… - Cellular …, 2023 - Elsevier
Cancer cells produce abnormal levels of reactive oxygen species (ROS) that contribute to
promote their malignant phenotype. In this framework, we hypothesized that the change in …
promote their malignant phenotype. In this framework, we hypothesized that the change in …
[HTML][HTML] Effects of animal venoms and toxins on hallmarks of cancer
Animal venoms are a cocktail of proteins and peptides, targeting vital physiological
processes. Venoms have evolved to assist in the capture and digestion of prey. Key venom …
processes. Venoms have evolved to assist in the capture and digestion of prey. Key venom …
Structure–function studies and mechanism of action of snake venom L-amino acid oxidases
A Ullah - Frontiers in pharmacology, 2020 - frontiersin.org
Snake venom L-amino acid oxidases (SV-LAAOs) are the least studied venom enzymes.
These enzymes catalyze the stereospecific oxidation of an L-amino acid to their …
These enzymes catalyze the stereospecific oxidation of an L-amino acid to their …
Protein Biofortification in Lentils (Lens culinaris Medik.) Toward Human Health
Lentil (Lens culinaris Medik.) is a nutritionally dense crop with significant quantities of
protein, low-digestible carbohydrates, minerals, and vitamins. The amino acid composition …
protein, low-digestible carbohydrates, minerals, and vitamins. The amino acid composition …
L-amino acid oxidase from snake venom and its anticancer potential
L-amino acid oxidase (LAAO) is a protein toxin commonly found in snake venom. It has
many applications, ranging from biotechnology to potential anticancer therapeutics. LAAO …
many applications, ranging from biotechnology to potential anticancer therapeutics. LAAO …
L-lysine α-oxidase: enzyme with anticancer properties
EV Lukasheva, G Babayeva, SS Karshieva… - Pharmaceuticals, 2021 - mdpi.com
L-lysine α-oxidase (LO), one of L-amino acid oxidases, deaminates L-lysine with the yield of
H2O2, ammonia, and α-keto-ε-aminocaproate. Multiple in vitro and in vivo studies have …
H2O2, ammonia, and α-keto-ε-aminocaproate. Multiple in vitro and in vivo studies have …
Venom Ontogeny in the Mexican Lance-Headed Rattlesnake (Crotalus polystictus)
As trophic adaptations, rattlesnake venoms can vary in composition depending on several
intrinsic and extrinsic factors. Ontogenetic changes in venom composition have been …
intrinsic and extrinsic factors. Ontogenetic changes in venom composition have been …