Are we there yet? Assessing the readiness of single-cell proteomics to answer biological hypotheses
AA Nitz, JH Giraldez Chavez, ZG Eliason… - Journal of Proteome …, 2024 - ACS Publications
Single-cell analysis is an active area of research in many fields of biology. Measurements at
single-cell resolution allow researchers to study diverse populations without losing …
single-cell resolution allow researchers to study diverse populations without losing …
The Future of Proteomics is Up in the Air: Can Ion Mobility Replace Liquid Chromatography for High Throughput Proteomics?
Y Jiang, D DeBord, H Vitrac, J Stewart… - Journal of Proteome …, 2024 - ACS Publications
The coevolution of liquid chromatography (LC) with mass spectrometry (MS) has shaped
contemporary proteomics. LC hyphenated to MS now enables quantification of more than …
contemporary proteomics. LC hyphenated to MS now enables quantification of more than …
Deep Learning Predicts Non-Normal Transmission Distributions in High-Field Asymmetric Waveform Ion Mobility (FAIMS) Directly from Peptide Sequence
Peptide ion mobility adds an extra dimension of separation to mass spectrometry-based
proteomics. The ability to accurately predict peptide ion mobility would be useful to expedite …
proteomics. The ability to accurately predict peptide ion mobility would be useful to expedite …
Intact protein barcoding enables one-shot identification of CRISPRi strains and their metabolic state
Detecting strain-specific barcodes with mass spectrometry can facilitate the screening of
genetically engineered bacterial libraries. Here, we introduce intact protein barcoding, a …
genetically engineered bacterial libraries. Here, we introduce intact protein barcoding, a …
Comprehensive overview of bottom-up proteomics using mass spectrometry
Proteomics is the large scale study of protein structure and function from biological systems
through protein identification and quantification.“Shotgun proteomics” or “bottom-up …
through protein identification and quantification.“Shotgun proteomics” or “bottom-up …