[HTML][HTML] Gut microbiota-derived bile acids in intestinal immunity, inflammation, and tumorigenesis
J Cai, L Sun, FJ Gonzalez - Cell host & microbe, 2022 - cell.com
Inflammatory bowel disease (IBD) and colorectal cancer (CRC) are heterogeneous intestinal
diseases that threaten the health of an increasing number of individuals as their lifestyles …
diseases that threaten the health of an increasing number of individuals as their lifestyles …
Microbial transformations of human bile acids
Bile acids play key roles in gut metabolism, cell signaling, and microbiome composition.
While the liver is responsible for the production of primary bile acids, microbes in the gut …
While the liver is responsible for the production of primary bile acids, microbes in the gut …
Bile acid metabolism and signaling, the microbiota, and metabolic disease
The diversity, composition, and function of the bacterial community inhabiting the human
gastrointestinal tract contributes to host health through its role in producing energy or …
gastrointestinal tract contributes to host health through its role in producing energy or …
How bile acids and the microbiota interact to shape host immunity
Bile acids are increasingly appearing in the spotlight owing to their novel impacts on various
host processes. Similarly, there is growing attention on members of the microbiota that are …
host processes. Similarly, there is growing attention on members of the microbiota that are …
Interactive relationships between intestinal flora and bile acids
X Guo, ES Okpara, W Hu, C Yan, Y Wang… - International Journal of …, 2022 - mdpi.com
The digestive tract is replete with complex and diverse microbial communities that are
important for the regulation of multiple pathophysiological processes in humans and …
important for the regulation of multiple pathophysiological processes in humans and …
Gut microbiota: A new target for T2DM prevention and treatment
L Liu, J Zhang, Y Cheng, M Zhu, Z **ao… - Frontiers in …, 2022 - frontiersin.org
Type 2 diabetes mellitus (T2DM), one of the fastest growing metabolic diseases, has been
characterized by metabolic disorders including hyperglycemia, hyperlipidemia and insulin …
characterized by metabolic disorders including hyperglycemia, hyperlipidemia and insulin …
Immunology of bile acids regulated receptors
Bile acids are steroids generated at the interface of host and intestinal microbiota. While
primary bile acids are generated in the liver from cholesterol metabolism, secondary bile …
primary bile acids are generated in the liver from cholesterol metabolism, secondary bile …
Taxonomic and environmental distribution of bacterial amino acid auxotrophies
Many microorganisms are auxotrophic—unable to synthesize the compounds they require
for growth. With this work, we quantify the prevalence of amino acid auxotrophies across a …
for growth. With this work, we quantify the prevalence of amino acid auxotrophies across a …
Another renaissance for bile acid gastrointestinal microbiology
JM Ridlon, HR Gaskins - Nature Reviews Gastroenterology & …, 2024 - nature.com
The field of bile acid microbiology in the gastrointestinal tract is going through a current
rebirth after a peak of activity in the late 1970s and early 1980s. This renewed activity is a …
rebirth after a peak of activity in the late 1970s and early 1980s. This renewed activity is a …
Physiological role of bile acids modified by the gut microbiome
Y Kiriyama, H Nochi - Microorganisms, 2021 - mdpi.com
Bile acids (BAs) are produced from cholesterol in the liver and are termed primary BAs.
Primary BAs are conjugated with glycine and taurine in the liver and then released into the …
Primary BAs are conjugated with glycine and taurine in the liver and then released into the …