The chronic wound milieu changes essential oils' antibiofilm activity—an in vitro and larval model study

M Brożyna, B Dudek, W Kozłowska, K Malec… - Scientific Reports, 2024 - nature.com
Abstract Essential Oils (EOs) are currently being researched as potential antibiofilm agents
to combat infections related to chronic wound biofilms. As documented in the literature, EOs' …

[HTML][HTML] Antimicrobial and cytotoxic activities of water-soluble isoxazole-linked 1, 3, 4-oxadiazole with delocalized charge: in vitro and in vivo results

B Dudek, U Bąchor, E Drozd-Szczygieł… - International Journal of …, 2023 - mdpi.com
The distinct structure of cationic organic compounds plays a pivotal role in enhancing their
water solubility, which in turn influences their bioavailability. A representative of these …

Investigating the Translational Value of Periprosthetic Joint Infection Models to Determine the Risk and Severity of Staphylococcal Biofilms

A Sekar, Y Fan, P Tierney, M McCanne… - ACS Infectious …, 2024 - ACS Publications
With the advent of antibiotic-eluting polymeric materials for targeting recalcitrant infections,
using preclinical models to study biofilms are crucial for improving the treatment efficacy in …

Comparison of antibiofilm activity of low-concentrated hypochlorites vs polyhexanide-containing antiseptic

J Paleczny, AF Junka, P Krzyżek… - Frontiers in cellular …, 2023 - frontiersin.org
Chronic wound infection is highly associated with morbidity and endangers the patient's life.
Therefore, wound care products must have a potent antimicrobial and biofilm-eradicating …

[HTML][HTML] The Potential Impact of Edible Fruit Extracts on Bacterial Nucleases in Preliminary Research—In Silico and In Vitro Insight

Ł Szeleszczuk, M Brożyna, B Dudek… - International Journal of …, 2025 - mdpi.com
The extracts from fruits of Chaenomeles japonica (Thunb.) Lindl. ex Spach (CJE), Cornus
mas L.(CME), and Hippophaё rhamnoides L.(HRE) are known inhibitors of a variety of …

Chronic Wound Milieu Challenges Essential Oils' Antibiofilm Activity

M Brożyna, W Kozłowska, K Malec, J Paleczny… - bioRxiv, 2023 - biorxiv.org
The treatment of infected non-healing wounds poses a significant challenge to
contemporary medicine. Essential oils (EOs) are being increasingly investigated as potential …

Investigating the translational value of Periprosthetic Joint Infection (PJI) models to determine the risk and severity of Staphylococcal biofilms

A Sekar, Y Fan, P Tierney, M McCanne, P Jones… - …, 2024 - pmc.ncbi.nlm.nih.gov
With the advent of antibiotic-eluting polymeric materials for targeting recalcitrant infections,
using preclinical models to study biofilm is crucial for improving the treatment efficacy in …

The intra-articular combined intravenous administration of antibiotics versus intravenous administration of antibiotics in patients with prosthetic joint infection: a …

T Zhang, R Kang, Y Yang, H Zhou, Y Shen, Y Li, L Qin… - 2024 - researchsquare.com
Purpose The purpose of this study was to compare the safety and effectiveness of combined
intra-articular and intravenous administration of antibiotics with intravenous administration of …