Obstructive sleep apnea: current perspectives

AM Osman, SG Carter, JC Carberry… - Nature and science of …, 2018 - Taylor & Francis
The prevalence of obstructive sleep apnea (OSA) continues to rise. So too do the health,
safety, and economic consequences. On an individual level, the causes and consequences …

International consensus statement on obstructive sleep apnea

JL Chang, AN Goldberg, JA Alt… - International forum of …, 2023 - Wiley Online Library
Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …

U-Sleep: resilient high-frequency sleep staging

M Perslev, S Darkner, L Kempfner, M Nikolic… - NPJ digital …, 2021 - nature.com
Sleep disorders affect a large portion of the global population and are strong predictors of
morbidity and all-cause mortality. Sleep staging segments a period of sleep into a sequence …

Symptom subtypes of obstructive sleep apnea predict incidence of cardiovascular outcomes

DR Mazzotti, BT Keenan, DC Lim… - American journal of …, 2019 - atsjournals.org
Rationale: Symptom subtypes have been described in clinical and population samples of
patients with obstructive sleep apnea (OSA). It is unclear whether these subtypes have …

Phenotypic subtypes of OSA: a challenge and opportunity for precision medicine

A Zinchuk, HK Yaggi - Chest, 2020 - Elsevier
Current strategies for the management of OSA reflect a one-size-fits-all approach. Diagnosis
and severity of OSA are based on the apnea-hypopnea index and treatment initiated with …

Polysomnography for obstructive sleep apnea should include arousal-based scoring: an American Academy of Sleep Medicine position statement

RK Malhotra, DB Kirsch, DA Kristo, EJ Olson… - Journal of clinical …, 2018 - jcsm.aasm.org
The diagnostic criteria for obstructive sleep apnea (OSA) in adults, as defined in the
International Classification of Sleep Disorders, Third Edition, requires an increased …

Hypoxic burden in obstructive sleep apnea: present and future

MA Martinez-Garcia, M Sánchez-de-la-Torre… - Archivos de …, 2023 - Elsevier
Conventional measures of obstructive sleep apnea (OSA) severity, such as the apnea-
hypopnea index (AHI) and oxygen desaturation index (ODI) are commonly used to quantify …

Severity of desaturations reflects OSA-related daytime sleepiness better than AHI

S Kainulainen, J Töyräs, A Oksenberg… - Journal of Clinical …, 2019 - jcsm.aasm.org
Study Objectives: The aim was to investigate how the severity of apneas, hypopneas, and
related desaturations is associated with obstructive sleep apnea (OSA)-related daytime …

Reinventing polysomnography in the age of precision medicine

DC Lim, DR Mazzotti, K Sutherland, JW Mindel… - Sleep medicine …, 2020 - Elsevier
For almost 50 years, sleep laboratories around the world have been collecting massive
amounts of polysomnographic (PSG) physiological data to diagnose sleep disorders, the …

Age estimation from sleep studies using deep learning predicts life expectancy

A Brink-Kjaer, EB Leary, H Sun, MB Westover… - NPJ digital …, 2022 - nature.com
Sleep disturbances increase with age and are predictors of mortality. Here, we present deep
neural networks that estimate age and mortality risk through polysomnograms (PSGs). Aging …