The role of Caenorhabditis elegans in the discovery of natural products for healthy aging

B Kirchweger, J Zwirchmayr, U Grienke… - Natural Product …, 2023 - pubs.rsc.org
Covering: 2012 to 2023 The human population is aging. Thus, the greatest risk factor for
numerous diseases, such as diabetes, cancer and neurodegenerative disorders, is …

Allopolyploidy expanded gene content but not pangenomic variation in the hexaploid oilseed Camelina sativa

KA Bird, JR Brock, PP Grabowski, AM Harder… - Genetics, 2025 - academic.oup.com
Myosin storage myopathy (MSM) is a rare skeletal muscle disorder caused by mutations in
the slow muscle/β-cardiac myosin heavy chain (MHC) gene. MSM missense mutations …

Leveraging a new data resource to define the response of Cryptococcus neoformans to environmental signals

YS Kang, J Jung, HL Brown, C Mateusiak… - Genetics, 2025 - academic.oup.com
Cryptococcus neoformans is an opportunistic fungal pathogen with a polysaccharide
capsule that becomes greatly enlarged in the mammalian host and during in vitro growth …

Potential of High-Spatiotemporal Resolution Live Cell Imaging for Drug Discovery and Development

Y Mimori-Kiyosue, T Koizumi, T Washio - Drug Development Supported by …, 2024 - Springer
Live cell imaging techniques play a vital role in drug development by providing dynamic and
spatiotemporal insights into cellular processes. These techniques enable researchers to …

Imaging and Quantifying Mitochondrial Morphology in C. elegans During Aging

J Kim, M Averbukh, A Alcala, RA Barahona… - Journal of Visualized …, 2025 - app.jove.com
Mitochondria, important cellular organelles found in most eukaryotic cells, are major sites of
energy production through aerobic respiration. Beyond this well-known role as the'cellular …

An effective method for quantification, visualization, and analysis of 3D cell shape during early embryogenesis

Z Li, Z Huang, J Cao, G Guan, Z Zhao… - Quantitative …, 2025 - Wiley Online Library
Embryogenesis is the most basic process in developmental biology. Effectively and simply
quantifying cell shape is challenging for the complex and dynamic 3D embryonic cells …

From alleles to adaptations: Investigating the genetic landscape of C. elegans in response to ethanol

MH van Wijk - 2024 - search.proquest.com
Alcohol use disorder (AUD) is a worldwide problem and the risk of develo** this disease
is partly genetically regulated. Ethanol responses are conserved among mammals and …

Untersuchung des mikrovillären Bürstensaums im C. elegans Darmepithel mittels Puls-RNAi

S Adler - 2024 - kups.ub.uni-koeln.de
Enterozyten, die den Metazoen-Darm auskleiden, besitzen an ihrer apikalen Oberfläche
Aktin-basierte Membranausstülpungen, so genannte Mikrovilli, um durch diese …

Evaluating polyglutamine protein aggregation and toxicity in transgenic Caenorhabditis elegans models of Huntington's disease

LM Cordeiro, FAA Soares… - Methods in cell …, 2025 - pubmed.ncbi.nlm.nih.gov
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder
characterized by a repeat of the cytosine-adenine-guanine trinucleotide (CAG) in the …

[PDF][PDF] UTILIZING REPEATED LED EXPOSURE TO MEASURE PHOTOBLEACHING kINETIC DECAy RATE Of ACRIDINE ORANGE

G Sanchez, C Lopez, A Flores-Torres… - Journal of …, 2023 - westmont.edu
Fluorescence photobleaching is the permanent loss of a fluorophore's ability to excite and
then emit photons. In this paper we show the development of a technique utilizing a …