The incorporation of a synthetic, catalytically competent metallocofactor into a protein
scaffold to generate an artificial metalloenzyme (ArM) has been explored since the late …

Highlights•Recent advances in the field of artificial metalloenzymes with a particular focus
on enantioselective catalysis are described.•New design strategies for artificial …

Artificial metalloenzymes (ArMs), which combine an abiotic metal cofactor with a protein
scaffold, catalyze various synthetically useful transformations. To complement the natural …

Artificial (transfer) hydrogenases have been developed for organic synthesis, but they rely
on precious metals. Native hydrogenases use Earth‐abundant metals, but these cannot be …

Rhodium compounds have been used as scaffold for enzyme inhibitors, modulators of
protein/protein interactions and of protein aggregation. These compounds have been …

The design of artificial hemoproteins that could catalyze selective oxidations using clean
oxidants such as O2 or H2O2 under ecocompatible conditions constitutes a real challenge …

The two lipocalins, β-lactoglobulin (βLg) and glycodelin (Gd), are possibly the most closely
related members of the large and widely distributed lipocalin family, yet their functions …

An anionic iron (III)-porphyrin–testosterone conjugate 1-Fe has been synthesized and fully
characterized. It has been further associated with a neocarzinostatin variant, NCS-3.24, to …

The status of high-accuracy studies of metalloenzymes application as catalysts in non-
natural compounds synthesis has been presented. The discussion is organized based on …

A series of amphiphilic ligands were designed and synthesized. The rhodium complexes
with the ligands were applied to the asymmetric transfer hydrogenation of broad range of …