Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#

MH Abdul-Aziz, JWC Alffenaar, M Bassetti… - Intensive care …, 2020 - Springer
Abstract Purpose This Position Paper aims to review and discuss the available data on
therapeutic drug monitoring (TDM) of antibacterials, antifungals and antivirals in critically ill …

From therapeutic drug monitoring to model‐informed precision dosing for antibiotics

SG Wicha, AG Märtson, EI Nielsen… - Clinical …, 2021 - Wiley Online Library
Therapeutic drug monitoring (TDM) and model‐informed precision dosing (MIPD) have
evolved as important tools to inform rational dosing of antibiotics in individual patients with …

Treatment of drug-resistant tuberculosis. An official ATS/CDC/ERS/IDSA clinical practice guideline

P Nahid, SR Mase, GB Migliori, G Sotgiu… - American journal of …, 2019 - atsjournals.org
Background: The American Thoracic Society, US Centers for Disease Control and
Prevention, European Respiratory Society, and Infectious Diseases Society of America …

Population pharmacokinetics and Bayesian dose adjustment to advance TDM of anti-TB drugs

MGG Sturkenboom, AG Märtson, EM Svensson… - Clinical …, 2021 - Springer
Tuberculosis (TB) is still the number one cause of death due to an infectious disease.
Pharmacokinetics and pharmacodynamics of anti-TB drugs are key in the optimization of TB …

A review of population pharmacokinetic analyses of linezolid

E Bandín-Vilar, L García-Quintanilla… - Clinical …, 2022 - Springer
In recent years, many studies on population pharmacokinetics of linezolid have been
conducted. This comprehensive review aimed to summarize population pharmacokinetic …

Therapeutic drug monitoring can improve linezolid dosing regimens in current clinical practice: a review of linezolid pharmacokinetics and pharmacodynamics

GG Rao, R Konicki, D Cattaneo… - Therapeutic drug …, 2020 - journals.lww.com
Linezolid is an antibiotic used to treat infections caused by drug-resistant gram-positive
organisms, including vancomycin-resistant Enterococcus faecium, multi-drug resistant …

Therapeutic drug monitoring in patients with tuberculosis and concurrent medical problems

AG Märtson, G Burch, S Ghimire… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction Therapeutic drug monitoring (TDM) has been recommended for treatment
optimization in tuberculosis (TB) but is only is used in certain countries eg USA, Germany …

Linezolid toxicity in patients with drug-resistant tuberculosis: a prospective cohort study

S Wasserman, JCM Brust… - Journal of …, 2022 - academic.oup.com
Background Linezolid is recommended for treating drug-resistant TB. Adverse events are a
concern to prescribers but have not been systematically studied at the standard dose, and …

Population pharmacokinetics of linezolid in tuberculosis patients: dosing regimen simulation and target attainment analysis

WA Alghamdi, MH Al-Shaer, G An… - Antimicrobial agents …, 2020 - journals.asm.org
The prolonged treatment duration for multidrug-resistant tuberculosis (MDR-TB) makes
linezolid dosing difficult because of adverse effects associated with long-term use. We …

Multidrug-resistant tuberculosis

K Dheda, F Mirzayev, DM Cirillo, Z Udwadia… - Nature Reviews …, 2024 - nature.com
Tuberculosis (TB) remains the foremost cause of death by an infectious disease globally.
Multidrug-resistant or rifampicin-resistant TB (MDR/RR-TB; resistance to rifampicin and …