Candidiasis: From cutaneous to systemic, new perspectives of potential targets and therapeutic strategies
Candidiasis is an infection caused by fungi from a Candida species, most commonly
Candida albicans. C. albicans is an opportunistic fungal pathogen typically residing on …
Candida albicans. C. albicans is an opportunistic fungal pathogen typically residing on …
Novel antifungals and treatment approaches to tackle resistance and improve outcomes of invasive fungal disease
Fungal infections are on the rise, driven by a growing population at risk and climate change.
Currently available antifungals include only five classes, and their utility and efficacy in …
Currently available antifungals include only five classes, and their utility and efficacy in …
Periodontitis is associated with the development of fungal sinusitis: A nationwide 12‐year follow‐up study
MG Kim, MG Kang, MG Lee, SJ Yang… - Journal of Clinical …, 2023 - Wiley Online Library
Aim The incidence of fungal sinusitis is increasing; however, its pathophysiology has not
been investigated previously. We investigate the effect of periodontitis on the incidence of …
been investigated previously. We investigate the effect of periodontitis on the incidence of …
Lung and gut microbiomes in pulmonary aspergillosis: Exploring adjunctive therapies to combat the disease
Species within the Aspergillus spp. cause a wide range of infections in humans, including
invasive pulmonary aspergillosis, chronic pulmonary aspergillosis, and allergic …
invasive pulmonary aspergillosis, chronic pulmonary aspergillosis, and allergic …
Harnessing bioengineered myeloid progenitors for precision immunotherapies
W Buys, ET Zambidis - npj Regenerative Medicine, 2023 - nature.com
Granulocytes and macrophages are the frontline defenders of the innate immune system.
These myeloid cells play a crucial role in not only eliminating pathogens and tumor cells, but …
These myeloid cells play a crucial role in not only eliminating pathogens and tumor cells, but …
How are granulocytes for transfusion best used? The past, the present and the future
S Morton, K Fleming… - British Journal of …, 2023 - Wiley Online Library
Granulocyte transfusions continue to be used in clinical practice, predominantly for treatment
of refractory infection in the setting of severe neutropenia. There is biological plausibility for …
of refractory infection in the setting of severe neutropenia. There is biological plausibility for …
Neutrophil swarming is crucial for limiting oral mucosal infection by Candida albicans
Oral mucosal colonization by Candida albicans is benign in healthy people but progresses
to deeper infection, known as oropharyngeal candidiasis, that may become disseminated …
to deeper infection, known as oropharyngeal candidiasis, that may become disseminated …
Neutrophil generation from hematopoietic progenitor cells and induced pluripotent stem cells (iPSCs): Potential applications
A Jafarzadeh, M Motaghi, SK Patra, Z Jafarzadeh… - Cytotherapy, 2024 - Elsevier
Neutrophils are the most frequent immune cell type in peripheral blood, performing an
essential role against pathogens. People with neutrophil deficiencies are susceptible to …
essential role against pathogens. People with neutrophil deficiencies are susceptible to …
Virus-associated fungal infections and lost immune resistance
N Sarden, BG Yipp - Trends in Immunology, 2023 - cell.com
Invasive fungal infections are an increasing threat to human health. Of recent concern is the
emergence of influenza-or SARS-CoV-2-virus-associated invasive fungal infections …
emergence of influenza-or SARS-CoV-2-virus-associated invasive fungal infections …