Natural killer (NK) cells comprise a unique population of innate lymphoid cells endowed with
intrinsic abilities to identify and eliminate virally infected cells and tumour cells. Possessing …

Since the early description of three patients with relapsed leukaemia after allogeneic
haematopoietic cell transplantation (HCT) who obtained complete remission after donor …

Chimeric antigen receptor (CAR)-modified natural killer (NK) cells show antileukemic activity
against acute myeloid leukemia (AML) in vivo. However, NK cell-mediated tumor killing is …

The last decade has seen steadfast progress in drug development in acute myeloid
leukemia (AML) which has moved progressively towards genomic-based therapy. With …

Brain metastatic cancer poses a significant clinical challenge, with limited treatment options
and poor prognosis for patients. In recent years, immunotherapy has emerged as a …

Simple Summary Allogeneic stem cell transplantation (allo-SCT) represents the only
potentially curative treatment for high-risk acute myeloid leukemia (AML) and …

Prophylactic donor lymphocyte infusion (DLI) starting at 6 months after T cell-depleted
allogeneic stem cell transplantation (TCD-alloSCT) can introduce a graft-versus-leukemia …

Introduction Unmodified donor lymphocyte infusions (DLI) after allogeneic stem cell
transplantation (alloSCT) can boost the beneficial Graft-versus-Leukemia (GvL) effect but …

Identification of immune phenotypes linked to durable graft-versus-leukemia (GVL) response
following donor lymphocyte infusions (DLI) is of high clinical relevance. In this prospective …

Chimerism analysis after allogeneic hematopoietic stem cell transplantation serves to
confirm engraftment, indicate relapse of hematologic malignancy, and attribute graft failure …