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Circulating miRNA analysis for cancer diagnostics and therapy
Successful treatment of cancer depends on early diagnosis and effective monitoring of
patients' response to therapy. Traditional tools based on tumor biopsies lack the sensitivity …
patients' response to therapy. Traditional tools based on tumor biopsies lack the sensitivity …
Multibiomarker panels in liquid biopsy for early detection of pancreatic cancer–a comprehensive review
Pancreatic ductal adenocarcinoma (PDAC) is frequently detected in late stages, which leads
to limited therapeutic options and a dismal overall survival rate. To date, no robust method …
to limited therapeutic options and a dismal overall survival rate. To date, no robust method …
Dual-mode SERS and electrochemical detection of miRNA based on popcorn-like gold nanofilms and toehold-mediated strand displacement amplification reaction
MicroRNA (miRNA) has emerged as one of the ideal target biomarker analytes for cancer
detection because its abnormal expression is closely related to the occurrence of many …
detection because its abnormal expression is closely related to the occurrence of many …
Long noncoding RNA UCA1 from hypoxia-conditioned hMSC-derived exosomes: a novel molecular target for cardioprotection through miR-873-5p/XIAP axis
L Sun, W Zhu, P Zhao, Q Wang, B Fan, Y Zhu… - Cell death & …, 2020 - nature.com
Exosomes (Exo) secreted from mesenchymal stem cells (hMSCs) are protective against
myocardial injury. The purpose of the study was to investigate the role and mechanisms by …
myocardial injury. The purpose of the study was to investigate the role and mechanisms by …
Considerations and suggestions for the reliable analysis of miRNA in plasma using qRT-PCR
E Ban, EJ Song - Genes, 2022 - mdpi.com
MicroRNAs (miRNAs) are promising molecules that can regulate gene expression, and their
expression level and type have been associated with early diagnosis, targeted therapy, and …
expression level and type have been associated with early diagnosis, targeted therapy, and …
[HTML][HTML] Biomarkers and lung cancer early detection: state of the art
Simple Summary Lung cancer is the leading cause of cancer death worldwide. Detecting
lung malignancies promptly is essential for any anticancer treatment to reduce mortality and …
lung malignancies promptly is essential for any anticancer treatment to reduce mortality and …
Platelet removal from human blood plasma improves detection of extracellular vesicle‐associated miRNA
JWP Bracht, M Los, MAJ van Eijndhoven… - Journal of …, 2023 - Wiley Online Library
Human blood plasma prepared by centrifugation contains not only extracellular vesicles
(EVs) but also platelets and erythrocyte ghosts (ery‐ghosts). Here we studied whether …
(EVs) but also platelets and erythrocyte ghosts (ery‐ghosts). Here we studied whether …
International liquid biopsy standardization alliance white paper
D Connors, J Allen, JD Alvarez, J Boyle… - Critical reviews in …, 2020 - Elsevier
The promise of precision medicine as a model to customize health care to the individual
patient is heavily dependent upon new genetic tools to classify and characterize diseases …
patient is heavily dependent upon new genetic tools to classify and characterize diseases …
Quantitative or digital PCR? A comparative analysis for choosing the optimal one for biosensing applications
This paper offers an exhaustive comparison of quantitative PCR (qPCR) and digital PCR
(dPCR) technologies, focusing on their critical roles in molecular diagnostics, ranging from …
(dPCR) technologies, focusing on their critical roles in molecular diagnostics, ranging from …
Plasma microRNAs as potential biomarkers in early Alzheimer disease expression
The microRNAs (miRNAs) are potential biomarkers for complex pathologies due to their
involvement in the regulation of several pathways. Alzheimer Disease (AD) requires new …
involvement in the regulation of several pathways. Alzheimer Disease (AD) requires new …