The integrity and functions of epithelial barriers depend on the formation of adherens
junctions (AJs) and tight junctions (TJs). A characteristic feature of AJs and TJs is their …

Intestinal epithelial barrier is critical for the maintenance of normal gut homeostasis and
disruption of this barrier may trigger or exaggerate mucosal inflammation. The actin …

The Perlecan-Semaphorin 3A-Plexin A1-Neuropilin-1 (PSPN) Complex at the cell surface of
prostate cancer (PCa) cells influences cell–cell cohesion and dyscohesion. We investigated …

Actin is highly conserved and it is the most widespread protein in eukaryotic cells. One of the
most important features of actin, which allows it to have many different functions, is its ability …

Bacterial pathogens have evolved multiple strategies to disassemble epithelial cell apical
junctional complexes (AJCs) and infect epithelial cells. Leptospirosis is a widespread …

Zonula occludens-2 (ZO-2) is a tight junction (TJ) cytoplasmic protein, whose localization
varies according to cell density and Ca2+ in the media. In cells cultured in low calcium (LC) …

Actin is one of the most abundant intracellular proteins, essential in every eukaryotic cell
type. Actin plays key roles in tissue morphogenesis, cell adhesion, muscle contraction, and …

Quantifying multi-molecular complex assembly in specific cytoplasmic compartments is
crucial to understand how cells use assembly/disassembly of these complexes to control …

Abstract β-actin mRNA localization is mediated through a 28-nucleotide sequence, located
in the 3'UTR region, known as the Zipcode sequence. Binding of Zipcode Binding Protein 1 …

Epithelial cells exhibit two major types of actin structures associated with intercellular
adhesions, branched actin networks and linear actin cables. Early during adherens junction …