RNA medicines represent a paradigm shift in treatment and prevention of critical diseases of
global significance, eg, infectious diseases. The highly successful messenger RNA (mRNA) …

The emergence of novel respiratory infections (eg, COVID-19) and expeditious development
of nanoparticle-based COVID-19 vaccines have recently reignited considerable interest in …

Abstract A Dry Powder Inhaler (DPI) is a technique as well as a device used to inhale
formulation which is in the form of dry powder, and is inhaled through the nose or mouth. It …

Dry powder inhalers (DPIs) can be used with a wide range of drugs such as small molecules
and biologics and offer several advantages for inhaled therapy. Early DPI products were …

Pulmonary delivery of therapeutic agents has been considered the desirable administration
route for local lung disease treatment. As the latest generation of therapeutic agents, nucleic …

Introduction Most lung diseases are serious conditions resulting from genetic and
environmental causes associated with high mortality and severe symptoms. Currently …

Tuberculosis (TB) is caused by Mycobacterium tuberculosis (M. tb) and is the second
leading cause of death from an infectious disease globally. The disease mainly affects the …

Background Pulmonary drug delivery is an efficient way to deliver drugs directly to the site of
action ie, lungs or to the blood circulation with minimum systemic effects. Recent emergence …

Pharmaceutical aerosols play a key role in the treatment of lung disorders, but also systemic
diseases, due to their ability to target specific areas of the respiratory system (RS). This …

Nisin ZP is an antimicrobial peptide (AMP) produced by the bacterium Lactococcus lactis,
and we have previously demonstrated anticancer activity in NSCLC (A549) cells. In this …