Engineering nano-drug biointerface to overcome biological barriers toward precision drug delivery

S Waheed, Z Li, F Zhang, A Chiarini, U Armato… - Journal of …, 2022 - Springer
The rapid advancement of nanomedicine and nanoparticle (NP) materials presents novel
solutions potentially capable of revolutionizing health care by improving efficacy …

[HTML][HTML] Extracellular vesicles in nanomedicine and regenerative medicine: a review over the last decade

S Moghassemi, A Dadashzadeh, MJ Sousa, H Vlieghe… - Bioactive materials, 2024 - Elsevier
Small extracellular vesicles (sEVs) are known to be secreted by a vast majority of cells.
These sEVs, specifically exosomes, induce specific cell-to-cell interactions and can activate …

Milk exosomes-mediated miR-31-5p delivery accelerates diabetic wound healing through promoting angiogenesis

C Yan, J Chen, C Wang, M Yuan, Y Kang, Z Wu… - Drug …, 2022 - Taylor & Francis
The refractory diabetic wound has remained a worldwide challenge as one of the major
health problems. The impaired angiogenesis phase during diabetic wound healing partly …

Extracellular vesicles as a drug delivery system: A systematic review of preclinical studies

PEM de Castilla, L Tong, C Huang, AM Sofias… - Advanced drug delivery …, 2021 - Elsevier
During the past decades, extracellular vesicles (EVs) have emerged as an attractive drug
delivery system. Here, we assess their pre-clinical applications, in the form of a systematic …

Emerging prospects of exosomes for cancer treatment: from conventional therapy to immunotherapy

GH Nam, Y Choi, GB Kim, S Kim, SA Kim… - Advanced …, 2020 - Wiley Online Library
Exosomes are a class of extracellular vesicles of around 100 nm in diameter that are
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …

Integrating natural compounds and nanoparticle‐based drug delivery systems: A novel strategy for enhanced efficacy and selectivity in cancer therapy

A Manzari‐Tavakoli, A Babajani, MM Tavakoli… - Cancer …, 2024 - Wiley Online Library
Cancer remains a leading cause of death worldwide, necessitating the development of
innovative and more effective treatment strategies. Conventional cancer treatments often …

Opportunities and challenges in enhancing the bioavailability and bioactivity of dietary flavonoids: A novel delivery system perspective

D Yuan, Y Guo, F Pu, C Yang, X **ao, H Du, J He, S Lu - Food Chemistry, 2024 - Elsevier
Flavonoids have multiple favorable bioactivities including antioxidant, anti-inflammatory, and
antitumor. Currently, flavonoid-containing dietary supplements are widely tested in clinical …

Advanced phytochemical-based nanocarrier systems for the treatment of breast cancer

VP Chavda, LV Nalla, P Balar, R Bezbaruah… - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer is a concern for the healthcare system. Even with the
advancement of science and technology, the current system for therapeutics and diagnostics …

Exosomes as a next-generation drug delivery system: An update on drug loading approaches, characterization, and clinical application challenges

F Mehryab, S Rabbani, S Shahhosseini, F Shekari… - Acta biomaterialia, 2020 - Elsevier
Exosomes are small nanoparticles secreted by almost all cells and have a well-known role
in intercellular communication. They are found in different body fluids and can also be …

[HTML][HTML] Progress of exosomes in the diagnosis and treatment of lung cancer

K Xu, C Zhang, T Du, ANA Gabriel, X Wang, X Li… - Biomedicine & …, 2021 - Elsevier
The incidence and mortality of lung cancer account for first place all over the world. Lung
cancer lacks early diagnostic biomarkers; lung cancer patients are usually diagnosed in …