The role of non-coding RNAs in oncology
FJ Slack, AM Chinnaiyan - Cell, 2019 - cell.com
For decades, research into cancer biology focused on the involvement of protein-coding
genes. Only recently was it discovered that an entire class of molecules, termed non-coding …
genes. Only recently was it discovered that an entire class of molecules, termed non-coding …
MicroRNA in lung cancer: role, mechanisms, pathways and therapeutic relevance
Lung cancer is the cardinal cause of cancer-related deaths with restricted recourse of
therapy throughout the world. Clinical success of therapies is not very promising due to-late …
therapy throughout the world. Clinical success of therapies is not very promising due to-late …
A study of miRNAs as cornerstone in lung cancer pathogenesis and therapeutic resistance: A focus on signaling pathways interplay
Lung cancer (LC) is the most common cancer-related death globally, and many efforts have
been made to improve the patient care of LC patients, as well as the development of efficient …
been made to improve the patient care of LC patients, as well as the development of efficient …
Targeted MDM2 degradation reveals a new vulnerability for p53-inactivated triple-negative breast cancer
Triple-negative breast cancers (TNBC) frequently inactivate p53, increasing their
aggressiveness and therapy resistance. We identified an unexpected protein vulnerability in …
aggressiveness and therapy resistance. We identified an unexpected protein vulnerability in …
Targeting noncoding RNAs in disease
BD Adams, C Parsons, L Walker… - The Journal of …, 2017 - Am Soc Clin Investig
Many RNA species have been identified as important players in the development of chronic
diseases, including cancer. Over the past decade, numerous studies have highlighted how …
diseases, including cancer. Over the past decade, numerous studies have highlighted how …
Lung cancer epigenetics: from knowledge to applications
M Duruisseaux, M Esteller - Seminars in cancer biology, 2018 - Elsevier
Lung cancer is the leading cause of cancer-related mortality worldwide. Advances in our
understanding of the genomics of lung cancer have led to substantial progress in the …
understanding of the genomics of lung cancer have led to substantial progress in the …
Dual role of microRNA-31 in human cancers; focusing on cancer pathogenesis and signaling pathways
Widespread changes in the expression of microRNAs in cancer result in abnormal gene
expression for the miRNAs that control those genes, which in turn causes changes to entire …
expression for the miRNAs that control those genes, which in turn causes changes to entire …
Methylated circulating tumor DNA in blood: power in cancer prognosis and response
K Warton, KL Mahon, G Samimi - Endocrine-related cancer, 2016 - erc.bioscientifica.com
The aim of the present study was to perform a systematic review of published studies to
provide a robust estimation of the use of procalcitonin (ProCT) as a diagnostic marker of …
provide a robust estimation of the use of procalcitonin (ProCT) as a diagnostic marker of …
Hypoxic tumor-derived exosomal miR-31-5p promotes lung adenocarcinoma metastasis by negatively regulating SATB2-reversed EMT and activating MEK/ERK …
F Yu, M Liang, Y Huang, W Wu, B Zheng… - Journal of Experimental & …, 2021 - Springer
Background Exosomes have emerged as critical mediators of intercellular communication.
Hypoxia is widely recognized as a key regulator of tumor aggressiveness, and significantly …
Hypoxia is widely recognized as a key regulator of tumor aggressiveness, and significantly …
Frontiers of MicroRNA signature in non-small cell lung cancer
X Zhu, M Kudo, X Huang, H Sui, H Tian… - Frontiers in Cell and …, 2021 - frontiersin.org
Lung cancer is the leading cause of cancer-related deaths worldwide and non-small cell
lung cancer (NSCLC) accounts for more than 80% of all lung cancer cases. Recent …
lung cancer (NSCLC) accounts for more than 80% of all lung cancer cases. Recent …