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Goods and bads of the endocannabinoid system as a therapeutic target: lessons learned after 30 years
The cannabis derivative marijuana is the most widely used recreational drug in the Western
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …
[HTML][HTML] The endocannabinoid system: a potential target for the treatment of various diseases
H Lowe, N Toyang, B Steele, J Bryant… - International journal of …, 2021 - mdpi.com
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …
balance in internal environment (temperature, mood, and immune system) and energy input …
[HTML][HTML] Cannabinoids and pain: new insights from old molecules
S Vučković, D Srebro, KS Vujović, Č Vučetić… - Frontiers in …, 2018 - frontiersin.org
Cannabis has been used for medicinal purposes for thousands of years. The prohibition of
cannabis in the middle of the 20th century has arrested cannabis research. In recent years …
cannabis in the middle of the 20th century has arrested cannabis research. In recent years …
Tooth whitening: From the established treatments to novel approaches to prevent side effects
J Rodríguez‐Martínez, M Valiente… - Journal of Esthetic …, 2019 - Wiley Online Library
Objective The aim is to review the most important aspects about tooth whitening treatments,
their side effects, and the new emerging approaches to overcome them. Overview This …
their side effects, and the new emerging approaches to overcome them. Overview This …
Mechanisms of acupuncture-electroacupuncture on persistent pain
R Zhang, L Lao, K Ren, BM Berman - Anesthesiology, 2014 - pmc.ncbi.nlm.nih.gov
In the last decade, preclinical investigations of electroacupuncture mechanisms on
persistent tissue-injury (inflammatory), nerve-injury (neuropathic), cancer, and visceral pain …
persistent tissue-injury (inflammatory), nerve-injury (neuropathic), cancer, and visceral pain …
Early phytocannabinoid chemistry to endocannabinoids and beyond
R Mechoulam, LO Hanuš, R Pertwee… - Nature Reviews …, 2014 - nature.com
Isolation and structure elucidation of most of the major cannabinoid constituents—including
Δ9-tetrahydrocannabinol (Δ9-THC), which is the principal psychoactive molecule in …
Δ9-tetrahydrocannabinol (Δ9-THC), which is the principal psychoactive molecule in …
Modulating the endocannabinoid system in human health and disease–successes and failures
The discovery of the endocannabinoid system, comprising the G‐protein coupled
cannabinoid 1 and 2 receptors (CB 1/2), their endogenous lipid ligands or …
cannabinoid 1 and 2 receptors (CB 1/2), their endogenous lipid ligands or …
CB2: a cannabinoid receptor with an identity crisis
CB2 was first considered to be the 'peripheral cannabinoid receptor'. This title was bestowed
based on its abundant expression in the immune system and presumed absence from the …
based on its abundant expression in the immune system and presumed absence from the …
Cannabinoids for treatment of chronic non‐cancer pain; a systematic review of randomized trials
ME Lynch, F Campbell - British journal of clinical pharmacology, 2011 - Wiley Online Library
Effective therapeutic options for patients living with chronic pain are limited. The pain
relieving effect of cannabinoids remains unclear. A systematic review of randomized …
relieving effect of cannabinoids remains unclear. A systematic review of randomized …
Endocannabinoid system: chemical characteristics and biological activity
B Rezende, AKN Alencar, GF de Bem… - Pharmaceuticals, 2023 - mdpi.com
The endocannabinoid system (eCB) has been studied to identify the molecular structures
present in Cannabis sativa. eCB consists of cannabinoid receptors, endogenous ligands …
present in Cannabis sativa. eCB consists of cannabinoid receptors, endogenous ligands …