Process intensification (PI) is a rapidly growing field of research and industrial development
that has already created many innovations in chemical process industry. PI is directed …

Reactive crystallization is not new, but there has been recent growth in its use as a means of
improving performance and sustainability of industrial processes. This review examines …

Crystallization, as a solid–liquid separation process, is employed to purify and isolate a
great diversity of crystalline pharmaceutical products. In recent years, continuous …

Molecular mechanisms and process kinetics of crystallizing concomitant polymorphs remain
poorly understood. Solvent‐mediated phase transformation and concomitant crystallization …

In the pharmaceutical industries, the requirements of rapid process development and
scalable design have made the tubular crystallizer a promising platform for continuous …

The challenges of insufficient residence time for crystal growing and transfer line blockage in
conventional continuous mixed‐suspension mixed‐product removal (MSMPR) operations …

Crystallization processes whose characteristic is dosing of one or multiple feeds are often
dominated by local phenomena at the feeding positions. This work applies a computational …

This article presents a new Extended Prediction Self-Adaptive Control (EPSAC) algorithm
based on the Just-in-Time Learning (JITL) method. In the proposed JITL-based EPSAC …

Crystallization is a highly selective unit operation capable of separating target molecules
from complex media. Its design requires precise solid-liquid equilibrium (SLE) data. The SLE …

This article introduces the application of a novel supersaturation control (SSC) approach for
the crystallization of heat‐sensitive materials. Traditional SSC implements parabolic …