Roles of Rac1-Dependent Intrinsic Forgetting in Memory-Related Brain Disorders: Demon or Angel

W Wang, Z Wang, J Cao, Y Dong, Y Chen - International Journal of …, 2023 - mdpi.com
Animals are required to handle daily massive amounts of information in an ever-changing
environment, and the resulting memories and experiences determine their survival and …

Single-nucleus transcriptomic map** of blast-induced traumatic brain injury in mice hippocampus

L Zhang, Q Yang, R Yuan, M Li, M Lv, L Zhang, X **e… - Scientific Data, 2023 - nature.com
As a significant type of traumatic brain injury (TBI), blast-induced traumatic brain injury (bTBI)
frequently results in severe neurological and psychological impairments. Due to its unique …

Role of Rho GTPases in stem cell regulation

Z Zhang, M Liu, Y Zheng - Biochemical Society Transactions, 2021 - portlandpress.com
The future of regenerative medicine relies on our understanding of stem cells which are
essential for tissue/organ generation and regeneration to maintain and/or restore tissue …

Single-Cell RNA Sequencing Reveals Molecular Features of Heterogeneity in the Murine Retinal Pigment Epithelium

RS Pandey, MP Krebs, MT Bolisetty… - International Journal of …, 2022 - mdpi.com
Transcriptomic analysis of the mammalian retinal pigment epithelium (RPE) aims to identify
cellular networks that influence ocular development, maintenance, function, and disease …

Overexpression of α-Klotho isoforms promotes distinct Effects on BDNF-Induced Alterations in Dendritic Morphology

MM Cararo-Lopes, R Sadovnik, A Fu, S Suresh… - Molecular …, 2024 - Springer
Abstract α-Klotho (α-Kl) is a modulator of aging, neuroprotection, and cognition.
Transcription of the Klotho gene produces two splice variants—a membrane protein (mKl) …

Rho GTPases in the amygdala—A switch for fears?

T Sarowar, AM Grabrucker - Cells, 2020 - mdpi.com
Fear is a fundamental evolutionary process for survival. However, excess or irrational fear
hampers normal activity and leads to phobia. The amygdala is the primary brain region …

Linkage of CDC42 and T-helper cell ratio with anxiety, depression and quality of life in ST-elevation myocardial infarction

X Wang, J Feng, S Luan, Y Zhou, S Zhang… - Biomarkers in …, 2024 - Taylor & Francis
Objective: To investigate the correlations between CDC42 and T-cell subsets concerning
anxiety, depression and quality of life in ST-elevation myocardial infarction patients …

Mitotic Activity and DNA Maintenance of Adult Neural Stem Cells is Regulated by Beclin1

A Kalinina, J Dhaliwal, Y Xue, M Vaculik… - bioRxiv, 2024 - biorxiv.org
Beclin1 is a tumor suppressor gene that can regulate proliferation under pathological
conditions. Whether Beclin1 has a role in regulating proliferation in physiological conditions …

Age-related neurodegeneration and cognitive impairments of NRMT1 knockout mice are preceded by misregulation of RB and expansion of the neural stem cell …

J Catlin, LN Marziali, B Rein, Z Yan, ML Feltri… - bioRxiv, 2021 - biorxiv.org
N-terminal methylation is an important post-translational modification that regulates
protein/DNA interactions and plays a role in many cellular processes, including DNA …

The role of stathmins 1/2 in ocular motor system axon guidance

R Gudjonsdottir - 2023 - sussex.figshare.com
Eye movements are crucial for the behaviour and survival of vertebrates and depend on
correct development of the ocular motor system, a well conserved system of three nerves …