Gender differences in cancer susceptibility: an inadequately addressed issue

MT Dorak, E Karpuzoglu - Frontiers in genetics, 2012 - frontiersin.org
The gender difference in cancer susceptibility is one of the most consistent findings in
cancer epidemiology. Hematologic malignancies are generally more common in males and …

The evolutionary causes and consequences of sex-biased gene expression

J Parsch, H Ellegren - Nature Reviews Genetics, 2013 - nature.com
Females and males often differ extensively in their physical traits. This sexual dimorphism is
largely caused by differences in gene expression. Recent advances in genomics, such as …

Ancient homomorphy of molluscan sex chromosomes sustained by reversible sex-biased genes and sex determiner translocation

W Han, L Liu, J Wang, H Wei, Y Li, L Zhang… - Nature Ecology & …, 2022 - nature.com
Contrary to classic theory prediction, sex-chromosome homomorphy is prevalent in the
animal kingdom but it is unclear how ancient homomorphic sex chromosomes avoid …

Sexual selection drives evolution and rapid turnover of male gene expression

PW Harrison, AE Wright, F Zimmer… - Proceedings of the …, 2015 - National Acad Sciences
The profound and pervasive differences in gene expression observed between males and
females, and the unique evolutionary properties of these genes in many species, have led to …

Sex-biased gene expression

S Grath, J Parsch - Annual review of genetics, 2016 - annualreviews.org
Methods of transcriptional profiling have made it possible to compare gene expression
between females and males on a genome-wide scale. Such studies have revealed that sex …

The transcriptional architecture of phenotypic dimorphism

JE Mank - Nature Ecology & Evolution, 2017 - nature.com
The profound differences in gene expression between the sexes are increasingly used to
study the molecular basis of sexual dimorphism, sexual selection and sexual conflict …

The genomics of sexual conflict

L Rowe, SF Chenoweth… - The American …, 2018 - journals.uchicago.edu
Sexual dimorphism is a substantial contributor to the diversity observed in nature, extending
from elaborate traits to the expression level of individual genes. Sexual conflict and sexually …

Sex-biased gene expression at homomorphic sex chromosomes in emus and its implication for sex chromosome evolution

B Vicoso, VB Kaiser, D Bachtrog - Proceedings of the …, 2013 - National Acad Sciences
Sex chromosomes originate from autosomes. The accumulation of sexually antagonistic
mutations on protosex chromosomes selects for a loss of recombination and sets in motion …

The roles of sexual selection and sexual conflict in sha** patterns of genome and transcriptome variation

NM Tosto, ER Beasley, BBM Wong, JE Mank… - Nature Ecology & …, 2023 - nature.com
Sexual dimorphism is one of the most prevalent, and often the most extreme, examples of
phenotypic variation within species, and arises primarily from genomic variation that is …

Sex-specific selection drives the evolution of alternative splicing in birds

TF Rogers, DH Palmer, AE Wright - Molecular Biology and …, 2021 - academic.oup.com
Males and females of the same species share the majority of their genomes, yet they are
frequently exposed to conflicting selection pressures. Gene regulation is widely assumed to …