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Oxytocin alleviates cognitive and memory impairments by decreasing hippocampal microglial activation and synaptic defects via OXTR/ERK/STAT3 pathway in a …
J Jiang, Y Zou, C **e, M Yang, Q Tong, M Yuan… - Brain, Behavior, and …, 2023 - Elsevier
Background Sepsis-associated encephalopathy (SAE) is a diffuse brain dysfunction,
characterized by cognitive and memory impairments closely linked to hippocampal …
characterized by cognitive and memory impairments closely linked to hippocampal …
Neuromodulatory functions exerted by oxytocin on different populations of hippocampal neurons in rodents
Oxytocin (OT) is a neuropeptide widely known for its peripheral hormonal effects (ie,
parturition and lactation) and central neuromodulatory functions, related especially to social …
parturition and lactation) and central neuromodulatory functions, related especially to social …
Oxytocin receptors in the Magel2 mouse model of autism: Specific region, age, sex and oxytocin treatment effects
The neurohormone oxytocin (OXT) has been implicated in the regulation of social behavior
and is intensively investigated as a potential therapeutic treatment in neurodevelopmental …
and is intensively investigated as a potential therapeutic treatment in neurodevelopmental …
Cell-specific regulation of the circadian clock by BMAL1 in the paraventricular nucleus: Implications for regulation of systemic biological rhythms
Circadian rhythms are internal biological rhythms driving temporal tissue-specific, metabolic
programs. Loss of the circadian transcription factor BMAL1 in the paraventricular nucleus …
programs. Loss of the circadian transcription factor BMAL1 in the paraventricular nucleus …
Heralding a new era of oxytocinergic research: New tools, new problems?
According to classic neuroendocrinology, hypothalamic oxytocin cells can be categorized
into parvo‐and magnocellular neurons. However, research in the last decade provided …
into parvo‐and magnocellular neurons. However, research in the last decade provided …
1, 5-anhydro-d-fructose exhibits satiety effects via the activation of oxytocin neurons in the paraventricular nucleus
1, 5-Anhydro-D-fructose (1, 5-AF) is a bioactive monosaccharide that is produced by the
glycogenolysis in mammalians and is metabolized to 1, 5-anhydro-D-glucitol (1, 5-AG). 1, 5 …
glycogenolysis in mammalians and is metabolized to 1, 5-anhydro-D-glucitol (1, 5-AG). 1, 5 …
Sex differences in MAGEL2 gene promoter methylation in high functioning autism-trends from a pilot study using nanopore Cas9 targeted long read sequencing
Background MAGEL2 is an autism susceptibility gene whose deficiency has been
associated with autism-related behaviors in animal models and in syndromic human autism …
associated with autism-related behaviors in animal models and in syndromic human autism …
MAGEL2 (patho‐) physiology and Schaaf–Yang syndrome
Schaaf–Yang syndrome (SYS) is a complex neurodevelopmental disorder characterized by
autism spectrum disorder, joint contractures, and profound hypothalamic dysfunction. SYS is …
autism spectrum disorder, joint contractures, and profound hypothalamic dysfunction. SYS is …
The Role of the Circadian Clock in the Paraventricular Nucleus of the Hypothalamus in Diurnal Energy Balance
R Van Drunen - 2024 - digitalcommons.library.tmc.edu
Circadian rhythms are internal biological rhythms that drive oscillations in physiology and
metabolism. Maintained at the level of individual cells throughout the body, the circadian …
metabolism. Maintained at the level of individual cells throughout the body, the circadian …
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Loss of cell cycle control usually drives rapid and uncontrollable tumor growth, which has
been considered an important feature for cancer cells (1). Cyclin D1, a key regulator of cell …
been considered an important feature for cancer cells (1). Cyclin D1, a key regulator of cell …