Single nucleus segmentation is a frequent challenge of microscopy image processing, since
it is the first step of many quantitative data analysis pipelines. The quality of tracking single …

Purpose: Since their first generation in 2013, the use of cerebral organoids has spread
exponentially. Today, the amount of generated data is becoming challenging to analyze …

The primary step in tissue cytometry is the automated distinction of individual cells
(segmentation). Since cell borders are seldom labeled, cells are generally segmented by …

Organoids are microtissues that recapitulate the complex structural organization and
functions of tissues and organs. Nanoparticles have several specific properties that must be …

Highly motile and functionally diverse immune cells orchestrate effective immune responses
through complex and dynamic cooperative behavior. Multiphoton intravital microscopy (MP …

Background Recent advances in tissue clearing techniques, combined with high-speed
image acquisition through light sheet microscopy, enable rapid three-dimensional (3D) …

Simple Summary The classical approach to study the immune response against a tumor was
mixing immune cells with tumor cell suspensions in several experimental settings. These …

Organoids offer a powerful model to study cellular self-organisation, the growth of specific
tissue morphologies in-vitro, and to assess potential medical therapies. However, the …

Introduction: Three-dimensional (3D) multicellular spheroids are fundamental in vitro tools
for studying in vivo tissues. Volume is the main feature used for evaluating the …

Background The segmentation of 3D cell nuclei is essential in many tasks, such as targeted
molecular radiotherapies (MRT) for metastatic tumours, toxicity screening, and the …