Potential role of flavonoids in treating chronic inflammatory diseases with a special focus on the anti-inflammatory activity of apigenin

R Ginwala, R Bhavsar, DGI Chigbu, P Jain, ZK Khan - Antioxidants, 2019 - mdpi.com
Inflammation has been reported to be intimately linked to the development or worsening of
several non-infectious diseases. A number of chronic conditions such as cancer, diabetes …

Flavonoids and their anti-diabetic effects: Cellular mechanisms and effects to improve blood sugar levels

RK Al-Ishaq, M Abotaleb, P Kubatka, K Kajo… - Biomolecules, 2019 - mdpi.com
Diabetes mellitus (DM) is a prevailing global health metabolic disorder, with an alarming
incidence rate and a huge burden on health care providers. DM is characterized by the …

Antidiabetic properties of dietary flavonoids: a cellular mechanism review

R Vinayagam, B Xu - Nutrition & metabolism, 2015 - Springer
Background Natural food products have been used for combating human diseases for
thousands of years. Naturally occurring flavonoids including flavones, flavonols, flavanones …

Molecular mechanisms of the anti-obesity and anti-diabetic properties of flavonoids

M Kawser Hossain, A Abdal Dayem, J Han… - International journal of …, 2016 - mdpi.com
Obesity and diabetes are the most prevailing health concerns worldwide and their incidence
is increasing at a high rate, resulting in enormous social costs. Obesity is a complex disease …

Beneficial effects of citrus flavonoids on cardiovascular and metabolic health

AM Mahmoud, RJ Hernandez Bautista… - Oxidative medicine …, 2019 - Wiley Online Library
The prevalence of cardiovascular disease (CVD) is increasing over time. CVD is a
comorbidity in diabetes and contributes to premature death. Citrus flavonoids possess …

Flavanones: Citrus phytochemical with health‐promoting properties

D Barreca, G Gattuso, E Bellocco, A Calderaro… - …, 2017 - Wiley Online Library
Citrus fruit and juices represent one of the main sources of compounds with a high potential
for health promoting properties. Among these compounds, flavanones (such as hesperetin …

[Retracted] Citrus Genus and Its Waste Utilization: A Review on Health‐Promoting Activities and Industrial Application

UM Khan, A Sameen, RM Aadil… - Evidence‐Based …, 2021 - Wiley Online Library
Citrus fruits such as oranges, grapefruits, lemons, limes, tangerines, and mandarins, whose
production is increasing every year with the rise of consumer demand, are among the most …

Hesperidin, a citrus flavonoid ameliorates hyperglycemia by regulating key enzymes of carbohydrate metabolism in streptozotocin-induced diabetic rats

R Sundaram, E Nandhakumar… - Toxicology …, 2019 - Taylor & Francis
The present study investigated the protective effect of hesperidin on carbohydrate
metabolizing enzymes in streptozotocin-induced diabetic rats. Hesperidin was administered …

Dietary polyphenols—Important non-nutrients in the prevention of chronic noncommunicable diseases. A systematic review

W Koch - Nutrients, 2019 - mdpi.com
The improvement of the social and economic conditions of society has eliminated the threat
of death from the majority of infectious diseases. However, the rapid progress of civilization …

[HTML][HTML] Hesperidin and hesperetin against heavy metal toxicity: Insight on the molecular mechanism of mitigation

AC Famurewa, K Renu, MA Eladl… - Biomedicine & …, 2022 - Elsevier
Toxic heavy metals (THMs) are non-essential hazardous environmental pollutants with
intractable health challenges in humans and animals. Exposure to lead (Pb), cadmium (Cd) …