Updating the striatal–pallidal wiring diagram

LZ Fang, MC Creed - Nature neuroscience, 2024 - nature.com
The striatal and pallidal complexes are basal ganglia structures that orchestrate learning
and execution of flexible behavior. Models of how the basal ganglia subserve these …

Inhibition and attention deficit hyperactivity disorder

HC Quay - Journal of abnormal child psychology, 1997 - Springer
This paper updates the author's earlier hypothesis that Attention Deficit Hyperactivity
Disorder (ADHD) reflects underactivity in Gray's Behavioral Inhibition System. Five areas of …

[HTML][HTML] Virtual deep brain stimulation: Multiscale co-simulation of a spiking basal ganglia model and a whole-brain mean-field model with The Virtual Brain

JM Meier, D Perdikis, A Blickensdörfer… - Experimental …, 2022 - Elsevier
Deep brain stimulation (DBS) has been successfully applied in various neurodegenerative
diseases as an effective symptomatic treatment. However, its mechanisms of action within …

Local and distant cortical responses to single pulse intracranial stimulation in the human brain are differentially modulated by specific stimulation parameters

AC Paulk, R Zelmann, B Crocker, AS Widge… - Brain Stimulation, 2022 - Elsevier
Background Electrical neuromodulation via direct electrical stimulation (DES) is an
increasingly common therapy for a wide variety of neuropsychiatric diseases. Unfortunately …

Closed-loop adaptive deep brain stimulation in Parkinson's disease: procedures to achieve it and future perspectives

S Wang, G Zhu, L Shi, C Zhang, B Wu… - Journal of …, 2023 - journals.sagepub.com
Parkinson's disease (PD) is a neurodegenerative disease with a heavy burden on patients,
families, and society. Deep brain stimulation (DBS) can improve the symptoms of PD …

Chronic intracranial recordings in the globus pallidus reveal circadian rhythms in Parkinson's disease

JN Cagle, T de Araujo, KA Johnson, J Yu… - Nature …, 2024 - nature.com
Circadian rhythms have been shown in the subthalamic nucleus (STN) in Parkinson's
disease (PD), but only a few studies have focused on the globus pallidus internus (GPi). This …

Globus pallidus internus (GPi) deep brain stimulation for Parkinson's disease: expert review and commentary

KLK Au, JK Wong, T Tsuboi, RS Eisinger, K Moore… - Neurology and …, 2021 - Springer
Introduction The globus pallidus internus (GPi) region has evolved as a potential target for
deep brain stimulation (DBS) in Parkinson's disease (PD). DBS of the GPi (GPi DBS) is an …

A review of cognitive outcomes across movement disorder patients undergoing deep brain stimulation

S Cernera, MS Okun, A Gunduz - Frontiers in neurology, 2019 - frontiersin.org
Introduction: Although the benefit in motor symptoms for well-selected patients with deep
brain stimulation (DBS) has been established, cognitive declines associated with DBS can …

Artifact characterization and a multipurpose template-based offline removal solution for a sensing-enabled deep brain stimulation device

LH Hammer, RB Kochanski, PA Starr… - Stereotactic and functional …, 2022 - karger.com
Background: The Medtronic “Percept” is the first FDA-approved deep brain stimulation (DBS)
device with sensing capabilities during active stimulation. Its real-world signal-recording …

[HTML][HTML] How do adenosine A2A receptors regulate motor function?

A Mori - Parkinsonism & related disorders, 2020 - Elsevier
Adenosine A 2A receptor antagonism is a new therapeutic strategy in the symptomatic
treatment of Parkinson's disease (PD). This review addresses how adenosine A 2A …