Dried blood spot (DBS) analysis has been introduced more and more into clinical practice to
facilitate Therapeutic Drug Monitoring (TDM). To assure the quality of bioanalytical methods …

Exposure to discrimination or unfair treatment has emerged as an important risk factor for
illness and disease that disproportionately affects racial and ethnic minorities. Discriminatory …

There is increasing interest in using dried blood spot (DBS) cards to extend the reach of
global health and disease surveillance programs to hard-to-reach populations …

The challenges in the diagnosis, prognosis, and monitoring of Gaucher disease (GD), an
autosomal recessive inborn error of glycosphingolipid metabolism, can negatively impact …

Abstract Microsampling, a reduced volume (< 50 μl) sampling method has successfully
gained attention at the International Conference on Harmonization (ICH) level. It has been …

Sample preparation is considered as the bottleneck step in bioanalysis because each
biological matrix has its own unique challenges and complexity. Competent sample …

Over the past few years, dried blood spot (DBS) technology has become a convenient tool in
both qualitative and quantitative biological analysis. DBS technology consists of a …

Inborn errors of metabolism (IEMs) are a group of inherited diseases with variable
incidences. IEMs are caused by disrupting enzyme activities in specific metabolic pathways …

This review advances the discussion about the future of laboratory medicine in the 2020s. In
five major topic areas: 1. the “big picture” of healthcare; 2. pre-analytical factors; 3. Analytical …

Sanfilippo syndrome is a group of rare, complex, and progressive neurodegenerative
lysosomal storage disorders that is characterized by childhood dementia. The clinical …