Epidemiology and risk factors of urothelial bladder cancer

M Burger, JWF Catto, G Dalbagni, HB Grossman… - European urology, 2013 - Elsevier
CONTEXT: Urothelial bladder cancer (UBC) is a disease of significant morbidity and
mortality. It is important to understand the risk factors of this disease. OBJECTIVE: To …

A guide to plasma membrane solute carrier proteins

MD Pizzagalli, A Bensimon… - The FEBS …, 2021 - Wiley Online Library
This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily
of transporter proteins and their roles in human cells. The SLC superfamily currently …

SLC transporters as therapeutic targets: emerging opportunities

L Lin, SW Yee, RB Kim, KM Giacomini - Nature reviews Drug discovery, 2015 - nature.com
Solute carrier (SLC) transporters—a family of more than 300 membrane-bound proteins that
facilitate the transport of a wide array of substrates across biological membranes—have …

A decade of GWAS results in lung cancer

Y Bossé, CI Amos - Cancer Epidemiology, Biomarkers & Prevention, 2018 - AACR
Genome-wide association studies (GWAS) were successful to identify genetic factors
robustly associated with lung cancer. This review aims to synthesize the literature in this field …

Genome-wide association study of bladder cancer reveals new biological and translational insights

S Koutros, LA Kiemeney, PP Choudhury, RL Milne… - European urology, 2023 - Elsevier
Background Genomic regions identified by genome-wide association studies (GWAS) for
bladder cancer risk provide new insights into etiology. Objective To identify new …

Autophagy controls BCG-induced trained immunity and the response to intravesical BCG therapy for bladder cancer

K Buffen, M Oosting, J Quintin, A Ng… - PLoS …, 2014 - journals.plos.org
The anti-tuberculosis-vaccine Bacillus Calmette-Guérin (BCG) is the most widely used
vaccine in the world. In addition to its effects against tuberculosis, BCG vaccination also …

The interplay between oxidative stress, inflammation and angiogenesis in bladder cancer development

P Wigner, R Grębowski, M Bijak, J Saluk-Bijak… - International Journal of …, 2021 - mdpi.com
In 2018, 550,000 people were diagnosed with bladder cancer (BC), of which nearly 200,000
people died. Moreover, men are 4 times more likely than women to be diagnosed with BC …

Epidemiology of bladder cancer

N Malats, FX Real - Hematology/oncology clinics, 2015 - hemonc.theclinics.com
Bladder cancer is mainly a disease of aging; its incidence and prevalence increase around
the sixth decade and peak in the seventh to eighth decade of life. It is the ninth most …

[HTML][HTML] Intravesical BCG in patients with non-muscle invasive bladder cancer induces trained immunity and decreases respiratory infections

JH van Puffelen, B Novakovic, L van Emst… - … for ImmunoTherapy of …, 2023 - ncbi.nlm.nih.gov
Background BCG is recommended as intravesical immunotherapy to reduce the risk of
tumor recurrence in patients with non-muscle invasive bladder cancer (NMIBC). Currently, it …

[HTML][HTML] Genetic prediction of male pattern baldness

SP Hagenaars, WD Hill, SE Harris, SJ Ritchie… - PLoS …, 2017 - journals.plos.org
Male pattern baldness can have substantial psychosocial effects, and it has been
phenotypically linked to adverse health outcomes such as prostate cancer and …